Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 5/20 | 0.65 |
| ▸ | EGFR | P00533 | 17/20 | 0.65 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.56 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.56 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
| ▸ | FBP1 | P09467 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | FLT4 | P35916 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | TEK | Q02763 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118271 | 0.93 | EGFR (0.75) | ERBB2EGFRKDREPHB4EPHA2 | |
| SCHEMBL29623483 | 0.93 | EGFR (0.75) | ERBB2EGFRKDREPHB4EPHA2 | |
| SCHEMBL12743401 | 0.88 | EGFR (0.73) | ERBB2EGFRKDREPHB4EPHA2 | |
| SCHEMBL29623405 | 0.88 | EGFR (0.72) | ERBB2EGFRKDREPHB4EPHA2 | |
| SCHEMBL186250 | 0.88 | EGFR (0.72) | ERBB2EGFRKDREPHB4EPHA2 | |
| SCHEMBL1943054 | 0.88 | EGFR (0.77) | ERBB2EGFRKDREPHB4AURKA | |
| Hydrochloric Acid SCHEMBL1446449 | 0.87 | EGFR (0.71) | ERBB2EGFRKDREPHB4EPHA2 | |
| SCHEMBL4421677 | 0.87 | EGFR (0.69) | ERBB2EGFRKDREPHB4EPHA2 | |
| SCHEMBL1446188 | 0.87 | ERBB2 (0.66) | ERBB2EGFRFBP1 | |
| SCHEMBL2762294 | 0.87 | EGFR (0.67) | ERBB2EGFRKDREPHB4EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146764-A2 | DISPENSING DEVICE | Boehringer Ingelheim International GmbH (DE) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008138628-A2 | DISPENSING DEVICE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-20 | — | — | WO | disclosed |