Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.58 |
| ▸ | MAOB | P27338 | 10/20 | 0.58 |
| ▸ | MAOA | P21397 | 8/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197035 | 1.00 | KDM1A (0.58) | KDM1AMAOBMAOACYP2C19CYP2B6 | |
| SCHEMBL15054151 | 0.90 | MAOB (0.52) | KDM1AMAOBMAOACYP2C19CYP2B6 | |
| SCHEMBL3195755 | 0.87 | KDM1A (0.58) | KDM1AMAOBMAOACYP2C19CYP2B6 | |
| Acetic Acid SCHEMBL27904810 | 0.81 | MAPT (0.49) | KDM1AMAOBMAOACYP2C19CYP2B6 | |
| SCHEMBL16163349 | 0.79 | KDM1A (0.55) | KDM1ACYP1A2CYP2D6CYP2C9LMNA | |
| SCHEMBL15054721 | 0.79 | KDM1A (0.55) | KDM1ACYP1A2CYP2D6CYP2C9LMNA | |
| SCHEMBL15054722 | 0.79 | KDM1A (0.55) | KDM1ACYP1A2CYP2D6CYP2C9LMNA | |
| SCHEMBL16163347 | 0.79 | KDM1A (0.55) | KDM1ACYP1A2CYP2D6CYP2C9LMNA | |
| SCHEMBL15054723 | 0.79 | KDM1A (0.55) | KDM1ACYP1A2CYP2D6CYP2C9LMNA | |
| SCHEMBL6629465 | 0.76 | SLC6A2 (0.48) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142505-A1 | SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | Pfizer, Inc. (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008120093-A1 | SULFONAMIDES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 2008-10-09 | — | — | WO | disclosed |