Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 20/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3463924 | 0.82 | CCR1 (0.75) | CCR1CYP2C19KCNH2 | |
| SCHEMBL12765632 | 0.82 | CCR1 (0.65) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3465885 | 0.81 | CCR1 (0.71) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1639706 | 0.81 | CCR1 (0.66) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3468971 | 0.80 | CCR1 (0.68) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1637609 | 0.80 | CCR1 (0.65) | CCR1CYP2C19KCNH2 | |
| SCHEMBL1639577 | 0.80 | CCR1 (0.69) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3879906 | 0.80 | CCR1 (0.58) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3465403 | 0.79 | CCR1 (1.00) | CCR1CYP2C19KCNH2 | |
| SCHEMBL3465690 | 0.79 | CCR1 (0.63) | CCR1CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155712-A1 | 3-(IMIDAZOLYL)-PYRAZOLOÝ3,4-B¨PYRIDINES | ChemoCentryx Inc (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-2155203-A1 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | ChemoCentryx Inc (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008147815-A1 | 3-(IMIDAZOLYL)-PYRAZOLO[3,4-B]PYRIDINES | CHEMOCENTRYX, INC. (US) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008147822-A1 | AZAINDAZOLE COMPOUNDS AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2008-12-04 | — | — | WO | disclosed |