Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.49 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.49 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.49 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18942413 | 0.99 | USP2 (0.51) | CA1CA2CA12CA4CA5A | |
| SCHEMBL18068230 | 0.92 | CA1 (0.51) | CA1CA2CA12CA4CA5A | |
| SCHEMBL18045641 | 0.92 | CA1 (0.51) | CA1CA2CA12CA4CA5A | |
| SCHEMBL21134954 | 0.92 | CA12 (0.61) | CA1CA2CA12CA4CA5A | |
| SCHEMBL21134971 | 0.92 | CA12 (0.61) | CA1CA2CA12CA4CA5A | |
| SCHEMBL18942039 | 0.92 | CA12 (0.61) | CA1CA2CA12CA4CA5A | |
| SCHEMBL22892186 | 0.92 | CA12 (0.61) | CA1CA2CA12CA4CA5A | |
| SCHEMBL18942030 | 0.92 | CA12 (0.61) | CA1CA2CA12CA4CA5A | |
| SCHEMBL2539365 | 0.91 | CA1 (0.49) | CA1CA2CA12CA4CA5A | |
| SCHEMBL22821460 | 0.90 | POLB (0.48) | CA1CA2CA12CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235036-A1 | SACCHARIDE LUPANE DERIVATIVES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Universita Palackeho v Olomouci (CZ) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009094958-A1 | SACCHARIDE LUPANE DERIVATIVES, THEIR USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2009-08-06 | — | — | WO | disclosed |