Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468368 | 0.97 | DHODH (0.58) | DHODH | |
| SCHEMBL468553 | 0.93 | DHODH (0.73) | DHODH | |
| SCHEMBL3668796 | 0.81 | DHODH (0.82) | DHODH | |
| SCHEMBL468702 | 0.80 | DHODH (0.79) | DHODH | |
| SCHEMBL3670557 | 0.80 | DHODH (0.71) | DHODH | |
| SCHEMBL468583 | 0.79 | DHODH (1.00) | DHODH | |
| SCHEMBL468622 | 0.78 | DHODH (1.00) | DHODH | |
| SCHEMBL468664 | 0.78 | DHODH (0.76) | DHODH | |
| SCHEMBL3666606 | 0.78 | DHODH (0.87) | DHODH | |
| SCHEMBL3670180 | 0.77 | DHODH (0.76) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210615-A1 | Combinations comprising methotrexate and DHODH inhibitors | Almirall, S.A. (ES) | 2010-07-28 | — | — | EP | claimed |