⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2227105 | 0.96 | — | — | |
| SCHEMBL10933443 | 0.82 | — | — | |
| SCHEMBL5181449 | 0.75 | — | — | |
| SCHEMBL2570303 | 0.72 | — | — | |
| SCHEMBL304888 | 0.70 | — | — | |
| SCHEMBL7290 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL853938 | 0.70 | — | — | |
| SCHEMBL4666457 | 0.67 | — | — | |
| Iodide SCHEMBL1726656 | 0.67 | — | — | |
| Fluoride SCHEMBL22032641 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580399-B2 | Geranyl flavonoid derivative with improved water solubility, a method for preparing the same, and a method for treating cancer using the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-02-28 | — | — | US | claimed |
| US-20160060239-A1 | GERANYL FLAVONOID DERIVATIVE WITH IMPROVED WATER SOLUBILITY, A METHOD FOR PREPARING THE SAME, AND A METHOD FOR TREATING CANCER USING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-03-03 | — | — | US | claimed |
| US-9580399-B2 | Geranyl flavonoid derivative with improved water solubility, a method for preparing the same, and a method for treating cancer using the same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-02-28 | — | — | US | disclosed |
| US-20160060239-A1 | GERANYL FLAVONOID DERIVATIVE WITH IMPROVED WATER SOLUBILITY, A METHOD FOR PREPARING THE SAME, AND A METHOD FOR TREATING CANCER USING THE SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-03-03 | — | — | US | disclosed |
| EP-2242742-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-20150239849-A1 | INHIBITORS OF BETA-SECRETASE | DOW AGROSCIENCES LLC | 2015-08-27 | — | — | US | disclosed |
| US-20150239849-A1 | INHIBITORS OF BETA-SECRETASE | DOW AGROSCIENCES LLC | 2015-08-27 | — | — | US | disclosed |
| US-9018391-B2 | Inhibitors of beta-secretase | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-04-28 | — | — | US | disclosed |
| WO-2014035860-A1 | INHIBITORS OF BETA-SECRETASE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-06 | — | — | WO | disclosed |
| US-20140057927-A1 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. | 2014-02-27 | — | — | US | disclosed |
| US-8343966-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-01-01 | — | — | US | disclosed |
| US-20040192693-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-09-30 | — | — | US | disclosed |
| US-5196531-A | Poly(N-cyclic iminoether), process for production thereof, thermosetting composition containing it and thermoset resin | TEIJIN LIMITED (JP) | 1993-03-23 | — | — | US | disclosed |
| EP-0487423-A1 | Benzoselenazolinone derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-05-27 | — | — | EP | disclosed |
| US-4485042-A | COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1984-11-27 | — | — | US | disclosed |
| US-4474988-A | ETHERIFICATION FROM CORRESPONDING ALCOHOL, ACID CATALYSTS | UNION CARBIDE CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| EP-0115071-A1 | Process for the production of bis-(N,N-dialkylamino)alkyl ethers and the use of said ethers | UNION CARBIDE CORPORATION (US) | 1984-08-08 | — | — | EP | disclosed |
| US-4342763-A | USEFUL AS ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS AND ANTITUSSIVE AGENTS | PROVESAN S.A. (CH) | 1982-08-03 | — | — | US | disclosed |
| US-4130650-A | 1-METHYL- OR DIMETHYL-AMINOETHOXY, 2-PYRIDYLVINYL-BENZENE | BOEHRINGER INGELHEIM GMBH (DE) | 1978-12-19 | — | — | US | disclosed |
| US-3933793-A | BACTERICIDES, VIRICIDES | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1976-01-20 | — | — | US | disclosed |