Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3528150 | 0.88 | AR (0.56) | ARCNR1 | |
| SCHEMBL3527116 | 0.87 | AR (0.54) | ARCNR1PGR | |
| SCHEMBL3526165 | 0.86 | AR (0.52) | ARCNR1PGR | |
| SCHEMBL1206915 | 0.84 | AR (0.47) | ARCNR1 | |
| SCHEMBL1207317 | 0.84 | AR (0.49) | ARCNR1PGR | |
| SCHEMBL3525124 | 0.84 | AR (0.54) | ARCNR1 | |
| SCHEMBL3985805 | 0.84 | AR (0.54) | ARCNR1 | |
| SCHEMBL3535057 | 0.84 | AR (0.50) | ARCNR1PGR | |
| SCHEMBL1208140 | 0.83 | AR (0.53) | ARCNR1 | |
| SCHEMBL12894791 | 0.83 | AR (0.46) | ARCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242746-A1 | HETEROCYCLICALLY-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | Sanofi-Aventis (FR) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009098000-A1 | HETEROCYCLICALLY-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |