⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15129956 | 0.97 | — | — | |
| Hydrogen Sulfide SCHEMBL27776379 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL15129732 | 0.97 | — | — | |
| Water SCHEMBL28785591 | 0.97 | — | — | |
| Bromide SCHEMBL14991518 | 0.97 | — | — | |
| SCHEMBL28166931 | 0.69 | — | — | |
| SCHEMBL27860020 | 0.67 | — | — | |
| SCHEMBL28798471 | 0.67 | — | — | |
| SCHEMBL446759 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL28176836 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943322-B | Azepine-nitrogen phosphine ligand, and preparation method and application thereof | 复旦大学 | 2023-09-29 | — | — | CN | claimed |
| CN-115768423-A | Inhibitors of EGFR, KRAS, BRAF and other targets and uses thereof | 密歇根大学董事会 | 2023-03-07 | — | — | CN | claimed |
| CN-110317855-A | The fluorescence detection method of identification IDO1 enzymatic activity and screening IDO1 enzyme inhibitor based on cell | 中国药科大学 | 2019-10-11 | — | — | CN | claimed |
| CN-108341821-A | A kind of synthetic method of epinastine hydrochloride | 千辉药业（安徽）有限责任公司 | 2018-07-31 | — | — | CN | claimed |
| EP-2804870-B1 | 2-AMINO-4,5,6,8-TETRAHYDROPYRAZOLO[3,4-b]THIAZOLO [4,5-d]AZEPINE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2016-11-30 | — | — | EP | claimed |
| EP-2804870-A1 | NOVEL 2-AMINO-4,5,6,8-TETRAHYDROPYRAZOLO[3,4-b]THIAZOLO [4,5-d]AZEPINE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX Pharma S.A. (CH) | 2014-11-26 | — | — | EP | claimed |
| WO-2013107862-A1 | NOVEL 2-AMINO-4,5,6,8-TETRAHYDROPYRAZOLO[3,4-b]THIAZOLO [4,5-d]AZEPINE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA S.A. (CH) | 2013-07-25 | — | — | WO | claimed |
| EP-2592932-A2 | NOVEL TETRAHYDROPYRAZOLO[3,4-B]AZEPINE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharma SA (CH) | 2013-05-22 | — | — | EP | claimed |
| WO-2012009001-A2 | NOVEL TETRAHYDROPYRAZOLO[3,4-B]AZEPINE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA S.A. (CH) | 2012-01-19 | — | — | WO | claimed |
| EP-2379553-A1 | BICYCLIC COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | Bristol-Myers Squibb Company (US) | 2011-10-26 | — | — | EP | claimed |
| WO-2010083141-A1 | BICYCLIC COMPOUNDS FOR THE REDUCTION OF BETA-AMYLOID PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-07-22 | — | — | WO | claimed |
| CN-1976679-A | Inhalant formulation containing sulfoalkyl ether cyclodextrin and corticosteroid | CYDEX INC (US) | 2007-06-06 | — | — | CN | claimed |
| US-6908926-B1 | Substituted imidazoles, their preparation and use | NOVO NORDISK A/S (DK) | 2005-06-21 | — | — | US | claimed |
| EP-0384677-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1993-12-01 | — | — | EP | claimed |
| EP-0384676-B1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1993-11-10 | — | — | EP | claimed |
| EP-0384677-A1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-08-29 | — | — | EP | claimed |
| EP-0384676-A1 | Alpha-adrenergic receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-08-29 | — | — | EP | claimed |
| WO-2026050214-A1 | ANTI-CLAUDIN, TLR AGONIST IMMUNOCONJUGATES AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2026-03-05 | — | — | WO | disclosed |
| US-4504480-A | DIAZABENZOCYCLOHEPTAFLUORENE DERIVATRIVES, ANTIDEPRESSANTS | BEECHAM GROUP P.L.C. (GB) | 1985-03-12 | — | — | US | disclosed |
| EP-0088575-A2 | Pentacyclic compounds | BEECHAM GROUP PLC (GB) | 1983-09-14 | — | — | EP | disclosed |