Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL9446943 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1TRPM8OPRM1 | |
| Octane SCHEMBL8813174 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1TRPM8OPRM1 | |
| SCHEMBL28163109 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1TRPM8OPRM1 | |
| Nonane SCHEMBL21751822 | 1.00 | TSHR (0.61) | TSHRTHRBDNM1TRPM8OPRM1 | |
| Hexane SCHEMBL1070241 | 0.96 | TSHR (0.54) | TSHRTHRBDNM1TRPM8OPRM1 | |
| Heptane SCHEMBL27573458 | 0.93 | TSHR (0.53) | TSHRTHRBDNM1TRPM8OPRM1 | |
| Hexane SCHEMBL5683602 | 0.92 | TSHR (0.54) | TSHRTHRBDNM1TRPM8OPRM1 | |
| Hexane SCHEMBL9287254 | 0.89 | TSHR (0.50) | TSHRTHRBDNM1TRPM8OPRM1 | |
| Pentane SCHEMBL1902886 | 0.88 | TSHR (0.58) | TSHRTHRBDNM1TRPM8OPRM1 | |
| Pentane SCHEMBL5683886 | 0.85 | TSHR (0.54) | TSHRTHRBDNM1TRPM8OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242498-A2 | SYNERGISTIC ANTIPARASITIC COMPOSITIONS AND SCREENING METHODS | Tyratech, Inc. (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009086471-A2 | SYNERGISTIC ANTIPARASITIC COMPOSITIONS AND SCREENING METHODS | TYRATECH, INC. (US) | 2009-07-09 | — | — | WO | disclosed |