Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | GRIN2D | O15399 | 8/20 | 0.60 |
| ▸ | GRIN3B | O60391 | 8/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 8/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.60 |
| ▸ | GRIN2C | Q14957 | 8/20 | 0.60 |
| ▸ | GRIN3A | Q8TCU5 | 8/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817701 | 1.00 | BCHE (0.65) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL1818727 | 0.91 | BCHE (0.56) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL13193018 | 0.91 | BCHE (0.56) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL29515771 | 0.88 | HTR2C (0.57) | BCHEKMT2A | |
| SCHEMBL1818790 | 0.86 | KMT2A (0.64) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL13193462 | 0.86 | KMT2A (0.64) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL30400654 | 0.85 | BCHE (0.60) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL13073125 | 0.85 | BCHE (0.60) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL7851268 | 0.84 | KMT2A (0.71) | BCHEKMT2AMAOATSHRGRIN2D | |
| SCHEMBL11819007 | 0.84 | KMT2A (0.63) | BCHEKMT2AMAOATSHRGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9163007-B2 | 5-substituted indazoles as kinase inhibitors | ABBVIE INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140343066-A1 | 5-SUBSTITUTED INDAZOLES AS KINASE INHIBITORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2014-11-20 | — | — | US | disclosed |
| US-8648069-B2 | 5-substituted indazoles as kinase inhibitors | ABBVIE INC. (US) | 2014-02-11 | — | — | US | disclosed |
| CN-101790526-A | 5-heteroaryl substituted indazoles as kinase inhibitors | ABBOTT GMBH & CO KG | 2010-07-28 | — | — | CN | disclosed |
| EP-2167491-A1 | 5-HETEROARYL SUBSTITUTED INDAZOLES AS KINASE INHIBITORS | Abbott Laboratories (US) | 2010-03-31 | — | — | EP | disclosed |
| US-20090203690-A1 | 5-SUBSTITUTED INDAZOLES AS KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2009-08-13 | — | — | US | disclosed |
| WO-2008154241-A1 | 5-HETEROARYL SUBSTITUTED INDAZOLES AS KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343066-A1 | 5-SUBSTITUTED INDAZOLES AS KINASE INHIBITORS | GSK3B, GSK3A, PIM3 | BCHE 3956/4885KMT2A 1399/4885MAOA 3445/4885 |
| US-20090203690-A1 | 5-SUBSTITUTED INDAZOLES AS KINASE INHIBITORS | GSK3B, GSK3A, PIM3 | BCHE 3956/4885KMT2A 1399/4885MAOA 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.