Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15092903 | 0.97 | MAPT (0.46) | MAPTOPRM1FDPSGPR84FFAR1 | |
| SCHEMBL8443918 | 0.97 | MAPT (0.46) | MAPTOPRM1FDPSGPR84FFAR1 | |
| SCHEMBL11044745 | 0.97 | MAPT (0.46) | MAPTOPRM1FDPSGPR84FFAR1 | |
| SCHEMBL5880658 | 0.92 | — | — | |
| SCHEMBL15766965 | 0.85 | TSHR (0.39) | MAPTOPRM1FDPSGPR84CA1 | |
| SCHEMBL11396254 | 0.84 | MAPT (0.41) | MAPTFDPSGPR84FFAR1LMNA | |
| SCHEMBL24614 | 0.79 | — | — | |
| SCHEMBL7911220 | 0.78 | MAPT (0.43) | MAPTOPRM1FDPSGPR84CA1 | |
| SCHEMBL1019048 | 0.77 | — | — | |
| SCHEMBL5177435 | 0.76 | MAPT (0.46) | MAPTOPRM1FDPSGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080124757-A1 | DISCRETE ACYLTRANSFERASES ASSOCIATED WITH TYPE I POLYKETIDE SYNTHASES AND METHODS OF USE | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2008-05-29 | — | — | US | claimed |
| US-20070026393-A1 | Detection of variations in the dna methylation profile | EPIGENOMICS AG (DE) | 2007-02-01 | — | — | US | claimed |
| US-20030175888-A1 | Discrete acyltransferases associated with type I polyketide synthases and methods of use | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-09-18 | — | — | US | claimed |
| EP-1084273-A1 | PROBES USED FOR GENETIC PROFILING | Genostic Pharma Limited (GB) | 2001-03-21 | — | — | EP | claimed |
| WO-1999064627-A2 | PROBES USED FOR GENETIC PROFILING | GENOSTIC PHARMA LIMITED (GB) | 1999-12-16 | — | — | WO | claimed |
| WO-1999064626-A2 | PROBES USED FOR GENETIC PROFILING | GENOSTIC PHARMA LIMITED (GB) | 1999-12-16 | — | — | WO | claimed |
| US-11702652-B2 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION A/S (DK) | 2023-07-18 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3305900-B1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION AS (DK) | 2021-07-21 | — | — | EP | disclosed |
| US-20200216836-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2020-07-09 | — | — | US | disclosed |
| US-20190330618-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION AS (DK) | 2019-10-31 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| US-10308971-B2 | Microorganism for expressing a human membrane protein | NOVOZYMES A/S (DK) | 2019-06-04 | — | — | US | disclosed |
| US-20030175888-A1 | Discrete acyltransferases associated with type I polyketide synthases and methods of use | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-09-18 | — | — | US | disclosed |
| WO-2003074654-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA) | SIRNA THERAPEURICS, INC (US) | 2003-09-12 | — | — | WO | disclosed |
| EP-1278892-A1 | DETECTION OF VARIATIONS IN THE DNA METHYLATION PROFILE | Epigenomics AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| WO-2001077373-A2 | DETECTION OF VARIATIONS IN THE DNA METHYLATION PROFILE | EPIGENOMICS AG (DE) | 2001-10-18 | — | — | WO | disclosed |
| EP-1084273-A1 | PROBES USED FOR GENETIC PROFILING | Genostic Pharma Limited (GB) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999064627-A2 | PROBES USED FOR GENETIC PROFILING | GENOSTIC PHARMA LIMITED (GB) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999064626-A2 | PROBES USED FOR GENETIC PROFILING | GENOSTIC PHARMA LIMITED (GB) | 1999-12-16 | — | — | WO | disclosed |