Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.48 |
| ▸ | FLT1 | P17948 | 3/20 | 0.44 |
| ▸ | FLT4 | P35916 | 3/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 4/20 | 0.42 |
| ▸ | MET | P08581 | 4/20 | 0.42 |
| ▸ | TEK | Q02763 | 4/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2710044 | 0.83 | KDR (0.52) | KDRFLT1FLT4RETPDGFRB | |
| SCHEMBL272878 | 0.82 | KDR (0.55) | KDRFLT1FLT4RETPDGFRB | |
| SCHEMBL2436216 | 0.81 | KDR (0.63) | KDRFLT1FLT4RETPDGFRB | |
| SCHEMBL275024 | 0.80 | KDR (0.60) | KDRFLT1FLT4RETPDGFRB | |
| SCHEMBL2434197 | 0.80 | KDR (0.70) | KDRFLT1FLT4 | |
| SCHEMBL2706646 | 0.80 | KDR (0.53) | KDRFLT1FLT4RETPDGFRB | |
| SCHEMBL987727 | 0.79 | KDR (0.64) | KDRFLT1FLT4RETPDGFRB | |
| SCHEMBL2708528 | 0.79 | KDR (0.64) | KDRFLT1FLT4RETPDGFRB | |
| SCHEMBL3580589 | 0.78 | KDR (0.52) | KDRFLT1FLT4RETPDGFRB | |
| SCHEMBL2706582 | 0.78 | KDR (0.53) | KDRFLT1FLT4RETPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146964-A2 | ETHERS OF NAPHTALENE CARBOXYLIC ACID AMIDES AS CANCER CURE | Novartis Ag (CH) | 2010-01-27 | — | — | EP | claimed |
| WO-2008125691-A2 | ETHERS OF NAPHTALENE CARBOXYLIC ACID AMIDES AS CANCER CURE | NOVARTIS AG (CH) | 2008-10-23 | — | — | WO | claimed |