SCHEMBL3668682

SCHEMBL3668682

CC(C)(C)OC(=O)C(c1ccccc1)(c1ccccc1)c1ccccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 6/20 0.46
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
ADRA1A P35348 1/20 0.39
OPRK1 P41145 1/20 0.39
KCNH2 Q12809 1/20 0.39
KIF11 P52732 1/20 0.39
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP1A2 P05177 1/20 0.34
ALOX15 P16050 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL491371 0.83 KCNN4 (0.64) KCNN4CYP2C19HIF1AMAPTKMT2A
Hydrogen Peroxide SCHEMBL27880626 0.83 KCNN4 (0.64) KCNN4CYP2C19HIF1AMAPTKMT2A
Hydrogen Sulfide SCHEMBL27788757 0.81 KCNN4 (0.62) KCNN4CYP2C19HIF1AMAPTKMT2A
Water SCHEMBL27886592 0.81 KCNN4 (0.62) KCNN4CYP2C19HIF1AMAPTKMT2A
SCHEMBL13427579 0.78 KCNN4 (0.48) KCNN4HTR2AHTR2CADRA1AOPRK1
SCHEMBL13865464 0.78 KCNN4 (0.52) KCNN4HTR2AHTR2CADRA1AOPRK1
SCHEMBL4462667 0.75 KCNN4 (0.64) KCNN4HTR2AHTR2CADRA1AOPRK1
SCHEMBL1147246 0.74 CYP2C19 (0.41) KCNN4HTR2AHTR2CADRA1AOPRK1
SCHEMBL30241792 0.73 KCNN4 (0.56) KCNN4KCNH2KIF11MAPTKMT2A
SCHEMBL28752641 0.72 KCNN4 (0.46) KCNN4HTR2AHTR2CADRA1AOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478247-A Preparation of cationic antibacterial glycolipid peptide GLP6 and application thereof in bacterial infection treatment 滨州医学院 2023-07-25 CN claimed
CN-118043339-A Antimicrobial peptidomimetics 巴斯利尔药物阿尔施维尔国际股份公司 2024-05-14 CN disclosed
CN-116478247-A Preparation of cationic antibacterial glycolipid peptide GLP6 and application thereof in bacterial infection treatment 滨州医学院 2023-07-25 CN disclosed
CN-115093463-A Beta-hairpin peptidomimetics 波利弗尔股份公司 2022-09-23 CN disclosed
CN-107847551-B Peptides having antiviral action and compositions comprising the same 珍白斯凯尔有限公司 2022-02-08 CN disclosed
CN-105324390-B Beta-hairpin peptidomimetics 波利弗尔股份公司 2021-10-19 CN disclosed
CN-107106651-B Peptide for treating eye disease and composition for treating eye disease comprising the same 珍白斯凯尔有限公司 2021-06-15 CN disclosed
CN-107405380-B Peptide for preventing hearing damage and composition comprising same 珍白斯凯尔有限公司 2021-04-20 CN disclosed
CN-105849119-B Beta-hairpin peptidomimetics 波利弗尔股份公司 2021-01-19 CN disclosed
CN-112135835-A Macrocyclization of peptidomimetics 华威大学 2020-12-25 CN disclosed
EP-2210305-A1 PROTON CONDUCTING MEMBRANES FOR FUEL CELLS HAVING A PROTON GRADIENT AND METHOD FOR PREPARING SAID MEMBRANES Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2010-07-28 EP disclosed
WO-2009040362-A1 PROTON CONDUCTING MEMBRANES FOR FUEL CELLS HAVING A PROTON GRADIENT AND METHOD FOR PREPARING SAID MEMBRANES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2009-04-02 WO disclosed
EP-1372686-A4 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS INC (US) 2004-01-02 EP disclosed
EP-1372686-A2 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS INC. (US) 2004-01-02 EP disclosed
WO-2001034635-A9 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS INC (US) 2002-08-01 WO disclosed
EP-1071442-A4 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS INC (US) 2002-06-05 EP disclosed
WO-2001034635-A2 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS, INC. (US) 2001-05-17 WO disclosed
EP-1071442-A1 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS INC. (US) 2001-01-31 EP disclosed
US-6015881-A COUPLING TOGETHER SPECIFIC SIDE-CHAIN PROTECTED PEPTIDE FRAGMENTS, DEPROTECTING AMINO TERMINUS, REACTING WITH ANOTHER PROTECTED PEPTIDE, MODIFYING AMINO TERMINUS TO ACETYL GROUP, DEPROTECTING SIDE-CHAINS; HIGH PURITY; GREATER LOAD TRIMERIS, INC. 2000-01-18 US disclosed
WO-1999048513-A1 METHODS AND COMPOSITIONS FOR PEPTIDE SYNTHESIS TRIMERIS, INC. (US) 1999-09-30 WO disclosed