Acetic Acid

Acetic Acid

SCHEMBL36700

CC(=O)[O-].CC(=O)[O-].CC(=O)[O-].[Rh+3]

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.89
CA4 P22748 3/20 0.58
LMNA P02545 2/20 0.50
TSHR P16473 2/20 0.46
THPO P40225 1/20 0.46
FFAR3 O14843 1/20 0.46
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
ALOX15 P16050 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
FAHD1 Q6P587 1/20 0.42
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CA2 P00918 1/20 0.36
PTGS1 P23219 1/20 0.36
MMP12 P39900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL29379737 1.00 CA1 (0.89) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL31458320 1.00 CA1 (0.89) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL31458334 1.00 CA1 (0.89) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL28782717 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL3136184 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL15011017 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL5079665 0.95 CA1 (0.80) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL116885 0.89 CA1 (0.89) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL1964006 0.89 CA1 (1.00) CA1CA4LMNATSHRTHPO
Acetic Acid SCHEMBL19962 0.89 CA1 (0.89) CA1CA4LMNATSHRTHPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5390 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118459390-B 3-Hydroxy oxindole derivative containing Z-type 1, 4-dicarbonyl olefin, and preparation method and application thereof SUN YAT-SEN UNIVERSITY (CN) 2026-05-26 CN claimed
US-12637469-B2 1H-pyrazole derivative and application thereof as dual target inhibitor of Syk and VEGFR2 OCUMENSION THERAPEUTICS (SUZHOU) CO., LTD. (CN) 2026-05-26 US claimed
CN-122059785-A Method for preparing 1, 1-disubstituted alkene by rhodium-catalyzed decarboxylation cracking 华南理工大学 2026-05-19 CN claimed
CN-119822938-B Method for synthesizing 2- (3-hydroxypropyl) cyclododecanone 万华化学集团股份有限公司 2026-05-19 CN claimed
CN-122039125-A Wood-derived carbon self-supporting transition metal core-shell hydrogen evolution catalyst and preparation method thereof 广西大学 2026-05-15 CN claimed
EP-4700035-A1 GLYCOSYLATION METHOD WITH PARTICIPATION OF TRIVALENT IODINE REAGENT Huazhong University of Science and Technology (CN) 2026-02-25 EP claimed
US-20260036897-A1 REPAIR PROCESS FOR CLEAR DEFECTS ON EUV PSM MASKS ZEISS CARL SMT GMBH (DE) 2026-02-05 US claimed
CN-120115179-A Bimetallic catalyst for purifying fume VOCs and preparation method and application thereof 北京市生态环境保护科学研究院 2025-06-10 CN claimed
CN-119530999-B Method for preparing polyetherimide fiber by oxidation method 东营市海科瑞林化工有限公司 2025-06-10 CN claimed
CN-120079392-A Manganese dioxide catalyst, preparation method and application 佛山市顺德区美的电热电器制造有限公司 2025-06-03 CN claimed
EP-0053688-B1 PROCESS FOR THE HYDROFORMULATION OF INSATURATED OLEFINIC COMPOUNDS BASF Aktiengesellschaft (DE) 1983-09-28 EP claimed
US-4400549-A CATALYST PREPARED IN SITU FROM PHODIUM ACETATE, TRIPHENYLPHOSPHINE AND CARBON MONOXIDE BASF AKTIENGESELLSCHAFT (DE) 1983-08-23 US claimed
US-4394299-A ACTIVATED CARBON SUPPORT, AMINE-PALLADIUM SALT-ACID, PHODIUM SALT-ALKALI NITRITE STANDARD OIL COMPANY (INDIANA) (US) 1983-07-19 US claimed
EP-0081824-A1 Processes for the production of antibiotic 1-oxadethiacephalosporins MEIJI SEIKA KAISHA LTD. (JP) 1983-06-22 EP claimed
US-4376724-A REDUCTION, CATALYST SUPPORTS SHOWA DENKO KABUSHIKI KAISHA (JP) 1983-03-15 US claimed
EP-0066627-A1 CATALYST FOR LOW-TEMPERATURE COMBUSTION AND PROCESS FOR ITS PREPARATION OSAKA GAS CO., LTD (JP) 1982-12-15 EP claimed
US-4299989-A Preparation of ketones UOP INC. (US) 1981-11-10 US claimed
US-4038325-A REFLUXING WITH RHODIUM COMPOUND IN ALCOHOL UOP INC. (US) 1977-07-26 US claimed
US-3981907-A Method of producing highly unsaturated compounds by reacting 1,3-conjugated diene compounds with derivatives of dimers of butadienes and products MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-09-21 US claimed
US-3947458-A RHODIUM CATALYST, REACTING NITROGEN COMPOUND, OLEFIN, CARBON MONOXIDE, WATER MONSANTO COMPANY (US) 1976-03-30 US claimed