Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | PPARD | Q03181 | 6/20 | 0.37 |
| ▸ | PPARA | Q07869 | 6/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylbutanoic Acid SCHEMBL5519850 | 0.91 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| 3-Methylbutanoic Acid SCHEMBL526714 | 0.91 | FFAR3 (0.65) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| 3-Methylbutanoic Acid SCHEMBL11650777 | 0.88 | FFAR3 (0.54) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| 3-Methylbutanoic Acid SCHEMBL28746566 | 0.88 | FFAR3 (0.54) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| 3-Methylbutanoic Acid SCHEMBL11446561 | 0.87 | FFAR3 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| 3-Methylbutanoic Acid SCHEMBL28545967 | 0.87 | TDP1 (0.52) | ALDH1A1TDP1SLC22A6ALOX15 | |
| Pyruvate SCHEMBL11244266 | 0.84 | FFAR3 (0.77) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| 3-Methylbutanoic Acid SCHEMBL18740744 | 0.82 | FFAR3 (0.48) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Hexanoate SCHEMBL27555941 | 0.82 | AKR1B1 (0.59) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Hexanoate SCHEMBL27645750 | 0.82 | AKR1B1 (0.64) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013187891-A1 | METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS | MARTIN ALAIN (US) | 2013-12-19 | — | — | WO | disclosed |
| EP-2187738-A1 | METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP OR DOWN REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS | Cellular Sciences, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009020582-A1 | METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP OR DOWN REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS | CELLULAR SCIENCES, INC. (US) | 2009-02-12 | — | — | WO | disclosed |