Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL10437036 | 0.86 | MEN1 (0.48) | KDM4EGAACYP2C9MEN1KMT2A | |
| SCHEMBL441202 | 0.84 | — | — | |
| SCHEMBL19956080 | 0.79 | MEN1 (0.52) | KDM4EGAACYP2C9MEN1KMT2A | |
| SCHEMBL30146940 | 0.78 | MEN1 (0.44) | KDM4EGAACYP2C9MEN1KMT2A | |
| SCHEMBL1830024 | 0.74 | — | — | |
| SCHEMBL17319684 | 0.72 | — | — | |
| Morpholine SCHEMBL1808505 | 0.71 | MEN1 (0.48) | KDM4EGAACYP2C9MEN1KMT2A | |
| SCHEMBL1782105 | 0.71 | HIF1A (0.50) | KDM4EGAACYP2C9HIF1AMAPT | |
| SCHEMBL1781839 | 0.71 | HIF1A (0.50) | KDM4EGAACYP2C9HIF1AMAPT | |
| SCHEMBL1780932 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808161-A | Method for radiolabeling biological compounds | 北京大学 | 2020-10-23 | — | — | CN | claimed |
| CN-104710504-A | Methods for generating radioimmunoconjugates | ACTINIUM PHARMACEUTICALS INC | 2015-06-17 | — | — | CN | claimed |
| CN-101674807-B | Compositions for reducing, ameliorating, treating, or preventing dry eye, and methods of making and using same | BAUSCH & LOMB | 2013-03-20 | — | — | CN | claimed |
| CN-114728074-A | Radiolabeling of anti-CD 45 immunoglobulins and methods of use thereof | 锕医药有限责任公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113195006-A | Combination therapy of radioimmunotherapy and immunodetection point therapy for the treatment of cancer | 锕医药有限责任公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-111808161-A | Method for radiolabeling biological compounds | 北京大学 | 2020-10-23 | — | — | CN | disclosed |
| CN-111050796-A | Treatment of hematologic malignancies | 锕医药股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-105377287-A | Kit for tumor imaging | UNIV JEFFERSON | 2016-03-02 | — | — | CN | disclosed |
| CN-104710504-A | Methods for generating radioimmunoconjugates | ACTINIUM PHARMACEUTICALS INC | 2015-06-17 | — | — | CN | disclosed |
| CN-102596258-B | Method for preparing a radioactive immunoconjugate | ACTINIUM PHARMACEUTICALS INC | 2015-01-28 | — | — | CN | disclosed |
| CN-101674807-B | Compositions for reducing, ameliorating, treating, or preventing dry eye, and methods of making and using same | BAUSCH & LOMB | 2013-03-20 | — | — | CN | disclosed |
| WO-2010016858-A2 | MOLECULAR IMAGING PROBES | CARESTREAM HEALTH, INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| EP-2148701-A2 | IMAGING CONTRAST AGENTS USING NANOPARTICLES | Carestream Health, Inc. (US) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008140475-A2 | IMAGING CONTRAST AGENTS USING NANOPARTICLES | CARESTREAM HEALTH, INC. (US) | 2008-11-20 | — | — | WO | disclosed |
| US-20020072667-A1 | MAGNETIC RESONANCE IMAGING | KUCHARCZYK JOHN (US) | 2002-06-13 | — | — | US | disclosed |