Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | IL1B | P01584 | 5/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006407 | 1.00 | GAA (0.40) | GAAIL1BP2RX7 | |
| SCHEMBL17065387 | 0.80 | MEN1 (0.47) | GAA | |
| SCHEMBL26126158 | 0.80 | MEN1 (0.47) | GAA | |
| SCHEMBL7277140 | 0.79 | MEN1 (0.45) | — | |
| SCHEMBL6377917 | 0.78 | CYP1A2 (0.59) | GAAP2RX7 | |
| SCHEMBL6377922 | 0.78 | CYP1A2 (0.59) | GAAP2RX7 | |
| SCHEMBL19585998 | 0.77 | MEN1 (0.50) | GAA | |
| SCHEMBL18785455 | 0.72 | DPP7 (0.43) | — | |
| SCHEMBL10641408 | 0.71 | CD274 (0.45) | P2RX7 | |
| SCHEMBL17065366 | 0.70 | KDM4E (0.43) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679350-A | Quinoline derivatives for the treatment of inflammatory diseases | ASTRAZENECA AB | 2010-03-24 | — | — | CN | disclosed |
| EP-2139879-A1 | QUINOLINE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | AstraZeneca AB (SE) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008114002-A1 | QUINOLINE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISEASES | ASTRAZENECA AB (SE) | 2008-09-25 | — | — | WO | disclosed |