⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12213960 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL11077270 | 0.97 | — | — | |
| SCHEMBL4135536 | 0.82 | — | — | |
| SCHEMBL10238113 | 0.82 | — | — | |
| SCHEMBL206350 | 0.72 | — | — | |
| SCHEMBL1228334 | 0.67 | — | — | |
| SCHEMBL17773098 | 0.63 | — | — | |
| SCHEMBL7380649 | 0.62 | — | — | |
| SCHEMBL7379165 | 0.62 | — | — | |
| SCHEMBL7380085 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220195115-A1 | FLUORINE-CONTAINING COPOLYMER | DAIKIN INDUSTRIES, LTD. (JP) | 2022-06-23 | — | — | US | disclosed |
| CN-108699053-B | 4-hydroxy-2-phenyl-1, 3-thiazol-5-yl methanone derivatives as TRPM8 antagonists | 东佩制药股份公司 | 2022-01-14 | — | — | CN | disclosed |
| EP-3394053-B1 | (4-HYDROXY-2-PHENYL-1,3-THIAZOL-5-YL) METHANONE DERIVATIVES AS TRPM8 ANTAGONISTS | DOMPE FARM SPA (IT) | 2019-08-21 | — | — | EP | disclosed |
| US-10246448-B2 | 4-hydroxy-2-phenyl-1,3-thiazol-5-yl methanone derivatives as TRPM8 antagonists | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2019-04-02 | — | — | US | disclosed |
| US-20180319785-A1 | 4-HYDROXY-2-PHENYL-1,3-THIAZOL-5-YL METHANONE DERIVATIVES AS TRPM8 ANTAGONISTS | DOMPÉ FARMACEUTICI S.P.A. (IT) | 2018-11-08 | — | — | US | disclosed |
| EP-3394053-A1 | 4-HYDROXY-2-PHENYL-1,3-THIAZOL-5-YL METHANONE DERIVATIVES AS TRPM8 ANTAGONISTS | Dompé farmaceutici S.p.A. (IT) | 2018-10-31 | — | — | EP | disclosed |
| WO-2017108632-A1 | 4-HYDROXY-2-PHENYL-1,3-THIAZOL-5-YL METHANONE DERIVATIVES AS TRPM8 ANTAGONISTS | DOMPE' FARMACEUTICI S.P.A. (IT) | 2017-06-29 | — | — | WO | disclosed |
| US-9540370-B2 | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors | ABBVIE DEUTSCHLAND GMBH & CO., KG. (DE) | 2017-01-10 | — | — | US | disclosed |
| US-20160194320-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS GLYCOGEN SYNTHASE KINASE-3 INHIBITORS | ABBVIE DEUTSCHLAND (DE) | 2016-07-07 | — | — | US | disclosed |
| US-9266855-B2 | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors | AbbVie Deutschland GmbH & Co. KG (DE) | 2016-02-23 | — | — | US | disclosed |
| EP-1918286-A1 | Thiazolhydrazides for treatment of neurodegenerative diseases | MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1861482-A2 | USE OF DIBENZANTHRONE AND ISODIBENZANTHRONE DERIVATIVES AS MARKING SUBSTANCES FOR LIQUIDS | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-05 | — | — | EP | disclosed |
| US-20070259881-A1 | Substituted Imidazo Ring Systems and Methods | COLEY PHARMACEUTICAL GROUP, INC. | 2007-11-08 | — | — | US | disclosed |
| US-20070149415-A1 | Power and lubricant additive concentrates containing at least one anthrachinone derivative as a marking substance | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-28 | — | — | US | disclosed |
| WO-2006097434-A2 | USE OF DIBENZANTHRONE AND ISODIBENZANTHRONE DERIVATIVES AS MARKING SUBSTANCES FOR LIQUIDS | BASF AKTIENGESELLSCHAFT (DE) | 2006-09-21 | — | — | WO | disclosed |
| EP-0288515-B1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | ISP INVESTMENTS INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| EP-0288515-A4 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | — | 1990-09-26 | — | — | EP | disclosed |
| US-4883655-A | HAIR OR SKIN CONDITIONING | GAF CORPORATION (US) | 1989-11-28 | — | — | US | disclosed |
| EP-0288515-A1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS. | GAF CORP (US) | 1988-11-02 | — | — | EP | disclosed |
| WO-1988002985-A1 | QUATERNIZED NITROGEN CONTAINING COMPOUNDS | GAF CORPORATION (US) | 1988-05-05 | — | — | WO | disclosed |