Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3672854 | 1.00 | MTOR (0.77) | MTOR | |
| SCHEMBL2905795 | 0.87 | MTOR (1.00) | MTOR | |
| SCHEMBL1218075 | 0.86 | MTOR (0.58) | MTOR | |
| SCHEMBL392081 | 0.85 | MTOR (0.72) | MTOR | |
| SCHEMBL392080 | 0.85 | MTOR (0.72) | MTOR | |
| SCHEMBL30363612 | 0.85 | MTOR (0.72) | MTOR | |
| SCHEMBL30405767 | 0.85 | MTOR (0.72) | MTOR | |
| SCHEMBL393314 | 0.85 | MTOR (0.72) | MTOR | |
| SCHEMBL8214027 | 0.85 | MTOR (0.72) | MTOR | |
| SCHEMBL391915 | 0.81 | MTOR (0.74) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262504-A1 | COMBINATION THERAPY 238 | AstraZeneca AB (SE) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009104019-A1 | COMBINATION THERAPY 238 | ASTRAZENECA AB (SE) | 2009-08-27 | — | — | WO | disclosed |