⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8614494 | 1.00 | — | — | |
| SCHEMBL13545374 | 1.00 | — | — | |
| SCHEMBL5260962 | 0.97 | — | — | |
| SCHEMBL12752809 | 0.72 | — | — | |
| SCHEMBL164048 | 0.71 | — | — | |
| SCHEMBL13493151 | 0.69 | — | — | |
| SCHEMBL12303963 | 0.69 | — | — | |
| SCHEMBL18197950 | 0.67 | — | — | |
| SCHEMBL19685376 | 0.67 | — | — | |
| SCHEMBL7274729 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787794-B2 | Aminothiazole compounds and methods using same | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2023-10-17 | — | — | US | disclosed |
| EP-4219486-A1 | NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE | Temple University of the Commonwealth System of Higher Education (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3571196-B1 | NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE | UNIV TEMPLE (US) | 2023-01-04 | — | — | EP | disclosed |
| US-10941126-B2 | Bridged bicycloalkyl-substituted aminothiazoles and their methods of use | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200071314-A1 | Novel Aminothiazole Compounds and Methods Using Same | UNIV TEMPLE (US) | 2020-03-05 | — | — | US | disclosed |
| US-10513516-B2 | Aminothiazole compounds and methods using same | Temple University—Of the Commonwealth System of Higher Education (US) | 2019-12-24 | — | — | US | disclosed |
| US-20190352272-A1 | Novel Bridged Bicycloalkyl-Substituted Aminothiazoles and Their Methods of Use | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2019-11-21 | — | — | US | disclosed |
| US-20180215750-A1 | Novel Aminothiazole Compounds and Methods Using Same | Temple University--of the Commonwealth System of Higher Education | 2018-08-02 | — | — | US | disclosed |
| WO-2018136766-A1 | NOVEL BRIDGED BICYCLOALKYL-SUBSTITUTED AMINOTHIZOLES AND THEIR METHODS OF USE | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-07-26 | — | — | WO | disclosed |
| US-20180110227-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| WO-2016102253-A1 | THIAZOLOPYRIDINONES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-30 | — | — | WO | disclosed |
| US-8410095-B2 | Thiazolopyrimidinone derivatives as PI3 kinase inhibitors | GLAXOSMITHKLINE LLC (US) | 2013-04-02 | — | — | US | disclosed |
| US-8410095-B2 | Thiazolopyrimidinone derivatives as PI3 kinase inhibitors | GLAXOSMITHKLINE LLC (US) | 2013-04-02 | — | — | US | disclosed |
| US-20120053147-A1 | THIAZOLOPYRIMIDINONE DERIVATIVES AS PI3 KINASE INHIBITORS | GLAXOSMITHKLINE LLC | 2012-03-01 | — | — | US | disclosed |
| WO-2010135504-A1 | THIAZOLOPYRIMIDINONE DERIVATIVES AS PI3 KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-11-25 | — | — | WO | disclosed |
| WO-2010135504-A1 | THIAZOLOPYRIMIDINONE DERIVATIVES AS PI3 KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2010-11-25 | — | — | WO | disclosed |
| US-7807676-B2 | Diketo-Piperazine and Piperidine derivatives as antiviral agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-10-05 | — | — | US | disclosed |
| WO-2008103357-A1 | FUNGICIDAL TRICYCLIC 1,2,4-TRIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-08-28 | — | — | WO | disclosed |
| US-20080139572-A1 | DIKETO-PIPERAZINE AND PIPERIDINE DERIVATIVES AS ANTIVIRAL AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 2008-06-12 | — | — | US | disclosed |
| US-4318913-A | 1,2,4-Triazole-3,5-diamine derivatives | GLAXO GROUP LIMITED (GB) | 1982-03-09 | — | — | US | disclosed |