Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.32 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | PPARD | Q03181 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053771 | 1.00 | TSHR (0.40) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL3482492 | 0.92 | — | — | |
| SCHEMBL3481866 | 0.81 | — | — | |
| SCHEMBL30758602 | 0.79 | TSHR (0.31) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL8384972 | 0.77 | TSHR (0.42) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL8385595 | 0.77 | TSHR (0.42) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL8385663 | 0.77 | TSHR (0.42) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL8385827 | 0.77 | TSHR (0.42) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL8381395 | 0.77 | TSHR (0.42) | TSHRTHRBALDH1A1LMNAHSD17B10 | |
| SCHEMBL8382272 | 0.77 | TSHR (0.42) | TSHRTHRBALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118125746-A | Self-repairing anti-cracking waterproof functional material and preparation method thereof | 浙江欣生新材料科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2020205740-A1 | POSS VISCOELASTIC HEMOSTATIC AGENTS | HYBRID PLASTICS, INCORPORATED (US) | 2020-10-08 | — | — | WO | disclosed |
| US-10758492-B2 | Two-dimensional polymeric structures and method for producing thereof | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2020-09-01 | — | — | US | disclosed |
| EP-2176361-B1 | SURFACE-TREATED METAL OXIDE PARTICLES | CABOT CORP (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20170258737-A1 | TWO-DIMENSIONAL POLYMERIC STRUCTURES AND METHOD FOR PRODUCING THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2017-09-14 | — | — | US | disclosed |
| EP-3193846-A1 | TWO-DIMENSIONAL POLYMERIC STRUCTURES AND METHOD FOR PRODUCING THEREOF | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2017-07-26 | — | — | EP | disclosed |
| US-20170174896-A1 | Surface-Treated Metal Oxide Particles | CABOT CORP (US) | 2017-06-22 | — | — | US | disclosed |
| WO-2016042484-A1 | TWO-DIMENSIONAL POLYMERIC STRUCTURES AND METHOD FOR PRODUCING THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-03-24 | — | — | WO | disclosed |
| US-20130129597-A1 | SURFACE-TREATED METAL OXIDE PARTICLES | CABOT CORPORATION (US) | 2013-05-23 | — | — | US | disclosed |
| US-8435474-B2 | colloidal silica powders or microstructure particles, coated with octyltriethoxysilane or 3-aminopropyltriethoxysilane, used in toners | CABOT CORPORATION (US) | 2013-05-07 | — | — | US | disclosed |
| EP-2176361-A1 | SURFACE-TREATED METAL OXIDE PARTICLES | Cabot Corporation (US) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009009011-A1 | SURFACE-TREATED METAL OXIDE PARTICLES | CABOT CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |
| US-20080070140-A1 | SURFACE-TREATED METAL OXIDE PARTICLES | CABOT CORPORATION (US) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258737-A1 | TWO-DIMENSIONAL POLYMERIC STRUCTURES AND METHOD FOR PRODUCING THEREOF | MLEC, EPCAM, VIM | TSHR 4159/4885THRB 3177/4885ALDH1A1 3212/4885 |
| US-10758492-B2 | Two-dimensional polymeric structures and method for producing thereof | MLEC, EPCAM, VIM | TSHR 4159/4885THRB 3177/4885ALDH1A1 3212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.