Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26980192 | 0.81 | TSHR (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28969506 | 0.79 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL1517252 | 0.79 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL10613522 | 0.77 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7771266 | 0.76 | LPAR6 (0.31) | — | |
| SCHEMBL23882527 | 0.75 | TSHR (0.49) | TSHRTHRB | |
| SCHEMBL8067583 | 0.75 | TSHR (0.49) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL6751821 | 0.75 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL536923 | 0.75 | TSHR (0.52) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3673665 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890171-B1 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | JOHNSON & JOHNSON VISION CARE (US) | 2010-12-22 | — | — | EP | claimed |
| EP-1890171-A2 | Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents | Johnson & Johnson Vision Care, Inc. (US) | 2008-02-20 | — | — | EP | claimed |