Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12743526 | 0.89 | EGFR (0.68) | EGFRERBB2 | |
| SCHEMBL208809 | 0.89 | EGFR (0.68) | EGFRERBB2 | |
| SCHEMBL29623459 | 0.89 | EGFR (0.68) | EGFRERBB2 | |
| SCHEMBL169874 | 0.89 | EGFR (0.68) | EGFRERBB2 | |
| SCHEMBL14490029 | 0.89 | EGFR (0.61) | EGFRERBB2 | |
| SCHEMBL14490028 | 0.89 | EGFR (0.61) | EGFRERBB2 | |
| SCHEMBL208730 | 0.88 | EGFR (0.66) | EGFRERBB2BRAF | |
| SCHEMBL208768 | 0.88 | EGFR (0.66) | EGFRERBB2BRAF | |
| SCHEMBL29623569 | 0.88 | EGFR (0.66) | EGFRERBB2BRAF | |
| SCHEMBL208731 | 0.88 | EGFR (0.66) | EGFRERBB2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162174-A1 | INHALER | Boehringer Ingelheim International GmbH (DE) | 2010-03-17 | — | — | EP | disclosed |
| WO-2009007068-A1 | INHALER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |