Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.69 |
| ▸ | PTAFR | P25105 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674252 | 1.00 | HRH3 (0.69) | HRH3PTAFRKCNH2 | |
| SCHEMBL3725592 | 0.93 | HRH3 (0.79) | HRH3PTAFRKCNH2 | |
| SCHEMBL3725594 | 0.93 | HRH3 (0.79) | HRH3PTAFRKCNH2 | |
| SCHEMBL4943972 | 0.92 | HRH3 (0.71) | HRH3PTAFRKCNH2 | |
| SCHEMBL3675222 | 0.90 | HRH3 (0.71) | HRH3PTAFRKCNH2 | |
| SCHEMBL3728327 | 0.89 | HRH3 (0.80) | HRH3PTAFRKCNH2 | |
| SCHEMBL3728329 | 0.89 | HRH3 (0.80) | HRH3PTAFRKCNH2 | |
| SCHEMBL3669116 | 0.87 | HRH3 (0.79) | HRH3PTAFRKCNH2 | |
| SCHEMBL3669119 | 0.87 | HRH3 (0.79) | HRH3PTAFRKCNH2 | |
| SCHEMBL3731705 | 0.86 | HRH3 (0.81) | HRH3PTAFRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155719-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | Wyeth LLC (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008147945-A1 | AZACYCLYLBENZAMIDE DERIVATIVES AS HISTAMINE-3 ANTAGONISTS | WYETH (US) | 2008-12-04 | — | — | WO | disclosed |