⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28274387 | 0.74 | CA1 (0.60) | — | |
| SCHEMBL21114488 | 0.74 | — | — | |
| SCHEMBL29557438 | 0.74 | — | — | |
| SCHEMBL27171 | 0.74 | — | — | |
| SCHEMBL7169460 | 0.74 | — | — | |
| SCHEMBL965530 | 0.74 | — | — | |
| SCHEMBL140330 | 0.74 | — | — | |
| SCHEMBL28324354 | 0.71 | — | — | |
| SCHEMBL3159805 | 0.70 | — | — | |
| SCHEMBL19066548 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234076-B | Preparation method of doxofylline | 湖北午时药业股份有限公司 | 2023-08-18 | — | — | CN | claimed |
| CN-116554121-A | Synthesis method of 2-isobutyl thiazole | 济南悟通生物科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-114853692-B | Preparation method of 2-aminothiazole | 广东省科学院化工研究所 | 2023-05-23 | — | — | CN | claimed |
| CN-115466176-A | Method for preparing chloroacetaldehyde, chloroacetaldehyde acetal, 2, 5-dihydroxy-1, 4-dithiane and 2-aminothiazole in anhydrous phase | 江西帝劢药业有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-114853692-A | Preparation method of 2-aminothiazole | 广东省科学院化工研究所 | 2022-08-05 | — | — | CN | claimed |
| CN-105985313-B | The method for being used to prepare chloroacetaldehyde acetal | 瓦克化学股份公司 | 2019-07-09 | — | — | CN | claimed |
| EP-3070082-B1 | PROCESS FOR PREPARING CHLOROACETALDEHYDE ACETALS | WACKER CHEMIE AG (DE) | 2018-05-09 | — | — | EP | claimed |
| US-9896428-B2 | Process for preparing chloroacetaldehyde acetals | WACKER CHEMIE AG (DE) | 2018-02-20 | — | — | US | claimed |
| US-20160272610-A1 | PROCESS FOR PREPARING CHLOROACETALDEHYDE ACETALS | WACKER CHEMIE AG (DE) | 2016-09-22 | — | — | US | claimed |
| EP-3070082-A1 | PROCESS FOR PREPARING CHLOROACETALDEHYDE ACETALS | Wacker Chemie AG (DE) | 2016-09-21 | — | — | EP | claimed |
| US-5576465-A | DEHYDROETHERIFICATION OF ACETALS OR KETALS BY HEATING | HUELS AKTIENGESELLSCHAFT (DE) | 1996-11-19 | — | — | US | claimed |
| EP-0247234-A1 | Process for the manufacture of acetals of chloro- or bromoacetaldehyde | National Starch and Chemical Corporation (US) | 1987-12-02 | — | — | EP | claimed |
| US-4642390-A | Process for the manufacture of acetals of chloroacetaldehyde | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1987-02-10 | — | — | US | claimed |
| JP-6199725-A | — | — | None | — | — | JP | disclosed |
| CN-116063163-B | Preparation method of 7- (benzyloxy) -2,4,5, 6-tetrahydro-1H-cyclobutadiene [ f ] indene-1-one | 上海毕臣生化科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113234076-B | Preparation method of doxofylline | 湖北午时药业股份有限公司 | 2023-08-18 | — | — | CN | disclosed |
| EP-0081856-B1 | PROCESS FOR THE PREPARATION OF CHLOROACETALDEHYDE-DIMETHYL ACETAL | Wacker-Chemie GmbH (DE) | 1985-03-13 | — | — | EP | disclosed |
| US-4440959-A | Process for the manufacture of chloroacetaldehyde dimethyl acetal | WACKER-CHEMIE GMBH (DE) | 1984-04-03 | — | — | US | disclosed |
| EP-0081856-A1 | Process for the preparation of chloroacetaldehyde-dimethyl acetal | Wacker-Chemie GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4137268-A | Method of preparing aminoacetaldehyde acetals by the hydrogenation of dialkoxyacetonitrile | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1979-01-30 | — | — | US | disclosed |