SCHEMBL3676043

SCHEMBL3676043

C=CCC1CCCN(c2ccc(NC[C@@H](O)CNC(=O)Oc3ccc(Cl)s3)cc2Cl)C1=O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16493754 0.93 F10 (0.34) F10
SCHEMBL3749556 0.88 F10 (0.40) F10
SCHEMBL3749552 0.88 F10 (0.40) F10
SCHEMBL3750324 0.80 F10 (0.43) F10
SCHEMBL3750328 0.80 F10 (0.43) F10
SCHEMBL16493883 0.79 F10 (0.52) F10
SCHEMBL3680139 0.74 F10 (0.51) F10
SCHEMBL3751249 0.71 F10 (0.37) F10
SCHEMBL3751255 0.71 F10 (0.37) F10
SCHEMBL76968 0.70 F10 (0.51) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167499-B1 SUBSTITUTED OXAZOLIDINONES AND USE THEREOF Bayer Pharma AG (DE) 2011-12-14 EP disclosed
EP-2167499-A2 SUBSTITUTED OXAZOLIDINONES AND USE THEREOF Bayer Schering Pharma AG (DE) 2010-03-31 EP disclosed
WO-2008155069-A2 SUBSTITUTED OXAZOLIDINONES AND USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2008-12-24 WO disclosed