Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.60 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.45 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4258257 | 0.93 | SLC2A1 (0.67) | SLC2A1P2RY12ALDH1A1MAPTHPGD | |
| 3-Chloroaniline SCHEMBL3676148 | 0.90 | SLC2A1 (0.61) | SLC2A1P2RY12ALDH1A1MAPTHPGD | |
| SCHEMBL3677907 | 0.84 | SLC2A1 (0.68) | SLC2A1P2RY12ALDH1A1MAOBP4HTM | |
| SCHEMBL3687374 | 0.84 | SLC2A1 (0.68) | SLC2A1P2RY12ALDH1A1MAPTHPGD | |
| SCHEMBL13930624 | 0.83 | SLC2A1 (0.67) | SLC2A1P2RY12ALDH1A1MAPTMAOB | |
| SCHEMBL31107157 | 0.83 | SLC2A1 (0.67) | SLC2A1P2RY12ALDH1A1MAPTMAOB | |
| SCHEMBL13930613 | 0.81 | SLC2A1 (0.62) | SLC2A1P2RY12ALDH1A1MAPTHPGD | |
| SCHEMBL31107155 | 0.81 | SLC2A1 (0.62) | SLC2A1P2RY12ALDH1A1MAPTHPGD | |
| SCHEMBL3683318 | 0.81 | SLC2A1 (0.65) | SLC2A1P2RY12ALDH1A1MAPTHPGD | |
| SCHEMBL4252921 | 0.81 | SLC2A1 (0.67) | SLC2A1P2RY12ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2182935-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. Hoffmann-Roche AG (CH) | 2010-05-12 | — | — | EP | claimed |
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | claimed |
| EP-2182935-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. Hoffmann-Roche AG (CH) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |