Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | GPR6 | P46095 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2160489 | 0.89 | SCD (0.49) | SCDSCD5SCN9A | |
| SCHEMBL2160557 | 0.85 | SCD (0.50) | SCDSCD5GPR6 | |
| SCHEMBL2161775 | 0.85 | SCD (0.54) | SCDPIN1SCD5 | |
| SCHEMBL2160657 | 0.85 | SCD (0.48) | SCDPIN1SCD5GPR6SCN9A | |
| SCHEMBL2160795 | 0.84 | SCD (0.57) | SCDSCD5GPR6 | |
| SCHEMBL2161363 | 0.83 | SCD (0.47) | SCDSCD5GPR6SCN9AHDAC3 | |
| SCHEMBL2161494 | 0.83 | SCD (0.49) | SCDSCD5GPR6SCN9AHDAC3 | |
| SCHEMBL2160875 | 0.83 | SCD (0.49) | SCDPIN1SCD5HDAC3HDAC2 | |
| SCHEMBL2161316 | 0.83 | SCD (0.48) | SCDSCD5GPR6SCN9AHDAC3 | |
| SCHEMBL2160513 | 0.82 | GPR6 (0.45) | SCDGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043052-A1 | AZETIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-04-22 | — | — | WO | disclosed |