Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677668 | 0.96 | S1PR1 (0.31) | S1PR1S1PR3KDM2BCYP2D6SLC6A2 | |
| SCHEMBL3674292 | 0.91 | CYP2D6 (0.32) | KDM2BCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3672849 | 0.91 | KDM2B (0.36) | S1PR1S1PR3KDM2B | |
| SCHEMBL3671585 | 0.86 | MRGPRX4 (0.34) | S1PR1S1PR3KDM2B | |
| SCHEMBL3742558 | 0.84 | S1PR1 (0.40) | S1PR1S1PR3EPHX2 | |
| SCHEMBL3669312 | 0.80 | MRGPRX4 (0.37) | KDM2BCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3672416 | 0.79 | MRGPRX4 (0.38) | S1PR1S1PR3EPHX2 | |
| SCHEMBL3675015 | 0.79 | S1PR1 (0.39) | S1PR1S1PR3EPHX2 | |
| SCHEMBL3672637 | 0.78 | KDM2B (0.35) | KDM2BEPHX2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL3674836 | 0.73 | MRGPRX4 (0.41) | S1PR1S1PR3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642296-B2 | 2-hydroxy-1-(4-hydroxymethyl-phenyl)-2-methyl-propan-1-one, have higher reactivity at the benzylic hydroxy group and do not have a tendency to yellowing; photocurable composition for pigmented or non-pigmented varnish surface coatings | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-01-05 | — | — | US | disclosed |
| US-20070240609-A1 | Photoinitiators | IGM GROUP B.V. (NL) | 2007-10-18 | — | — | US | disclosed |
| EP-1763499-B1 | NEW PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-09-26 | — | — | EP | disclosed |
| EP-1763499-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005100292-A1 | NEW PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-10-27 | — | — | WO | disclosed |