SCHEMBL3676642

SCHEMBL3676642

CCCCC(OC(=O)/C=C/C(=O)O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 7/20 0.57
POLB P06746 1/20 0.43
NOS2 P35228 1/20 0.40
CTSK P43235 1/20 0.40
CA2 P00918 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
MDM4 O15151 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
MDM2 Q00987 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4346781 1.00 HCAR2 (0.57) HCAR2POLBNOS2CTSKCA2
SCHEMBL3676644 1.00 HCAR2 (0.57) HCAR2POLBNOS2CTSKCA2
SCHEMBL10711253 0.94 HCAR2 (0.55) HCAR2ALDH1A1LMNAMAPTZDHHC2
SCHEMBL10711250 0.94 HCAR2 (0.55) HCAR2ALDH1A1LMNAMAPTZDHHC2
SCHEMBL9419967 0.91 HCAR2 (0.60) HCAR2NOS2ALDH1A1CYP3A4MDM4
SCHEMBL9419971 0.91 HCAR2 (0.60) HCAR2NOS2ALDH1A1CYP3A4MDM4
SCHEMBL9420058 0.91 HCAR2 (0.60) HCAR2NOS2ALDH1A1CYP3A4MDM4
SCHEMBL27216283 0.85 HCAR2 (0.64) HCAR2POLBNOS2ALDH1A1CYP3A4
SCHEMBL3482642 0.85 HCAR2 (0.64) HCAR2POLBNOS2ALDH1A1CYP3A4
SCHEMBL3482700 0.85 HCAR2 (0.64) HCAR2POLBNOS2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154530-A1 MODIFIED MONOCYTES/MACROPHAGES/DENDRITIC CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTORS AND USES IN DISEASES AND DISORDERS ASSOCIATED WITH PROTEIN AGGREGATES UNIV PENNSYLVANIA (US) 2025-05-15 US disclosed
EP-2119744-B1 TWO-COMPONENT CURING COMPOSITION SUNSTAR ENGINEERING INC (JP) 2019-06-05 EP disclosed
US-20100016486-A1 TWO-COMPONENT HARDENING COMPOSITION SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2010-01-21 US disclosed
EP-1655346-B1 TWO-PART CURABLE COMPOSITION SUNSTAR ENGINEERING INC (JP) 2009-12-09 EP disclosed
US-7622525-B2 Two-part curable composition SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2009-11-24 US disclosed
EP-2119744-A1 TWO-COMPONENT HARDENING COMPOSITION Sunstar Giken Kabushiki Kaisha (JP) 2009-11-18 EP disclosed
US-20060293437-A1 Two-part curable composition SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2006-12-28 US disclosed
EP-1655346-A1 TWO-PART CURABLE COMPOSITION SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 2006-05-10 EP disclosed