Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.65 |
| ▸ | CDC25A | P30304 | 4/20 | 0.63 |
| ▸ | POLA1 | P09884 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.55 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.54 |
| ▸ | OSBP | P22059 | 1/20 | 0.52 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MDM4 | O15151 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20419965 | 0.90 | CYP2D6 (0.64) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL24041178 | 0.90 | CYP2D6 (0.64) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL24041915 | 0.89 | CYP2D6 (0.60) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL24041169 | 0.89 | CYP2D6 (0.60) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL24041168 | 0.88 | CYP2D6 (0.61) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL24041170 | 0.88 | CYP2D6 (0.61) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL24041923 | 0.88 | CYP2D6 (0.61) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL24041175 | 0.87 | CYP2D6 (0.53) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL20419967 | 0.87 | CYP2D6 (0.53) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL22258801 | 0.86 | CYP2D6 (0.59) | CYP2D6CYP2C19INPP5DCDC25APOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781599-B2 | economical; nontoxic; high yield; industrial scale; Grignard reaction; iron catalyst (FeCl3) and a diamine (ethylenediamine); cross-coupling of alkyl halide and aromatic organometallic; primary or secondary alkyl substituents; phenylcycloheptane from bromocycloheptane and phenyl magnesium bromide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-08-24 | — | — | US | disclosed |
| US-20070123734-A1 | Process for production of aromatic compounds | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2007-05-31 | — | — | US | disclosed |
| EP-1724248-A1 | PROCESS FOR PRODUCTION OF AROMATIC COMPOUNDS | Japan Science and Technology Agency (JP) | 2006-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123734-A1 | Process for production of aromatic compounds | C9, C5, C1S | CYP2D6 37/4885CYP2C19 53/4885INPP5D 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.