Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 11/20 | 0.55 |
| ▸ | CDK2 | P24941 | 7/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.55 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.50 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.50 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.50 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099130 | 0.89 | CDK1 (0.69) | CDK1CDK2CDK5CSNK1DCLK2 | |
| SCHEMBL7016096 | 0.82 | CDK2 (0.63) | CDK1CDK2CDK5CCNE1CCNE2 | |
| SCHEMBL7008070 | 0.74 | CDK1 (0.57) | CDK1CDK2CDK5CSNK1DCLK2 | |
| SCHEMBL7014201 | 0.73 | CDK1 (0.67) | CDK1CDK2CDK5CSNK1DCLK2 | |
| SCHEMBL3686340 | 0.72 | CDK2 (0.78) | CDK1CDK2CDK5CSNK1DCLK2 | |
| SCHEMBL13498145 | 0.72 | CDK5 (0.69) | CDK1CDK2CDK5CSNK1DCLK2 | |
| SCHEMBL7016271 | 0.71 | CDK1 (0.65) | CDK1CDK2CDK5CSNK1DCLK2 | |
| SCHEMBL1216905 | 0.71 | CDK1 (1.00) | CDK1CDK2CDK5CSNK1DCLK2 | |
| SCHEMBL13497833 | 0.71 | CDK5 (0.68) | CDK1CDK2CDK5CSNK1DCLK2 | |
| SCHEMBL5827674 | 0.69 | CDK2 (1.00) | CDK1CDK2CDK5DYRK1ACCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764118-B1 | Polymer coating for medical devices | GILEAD PALO ALTO INC (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-1937328-B1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS INC (US) | 2009-08-26 | — | — | EP | disclosed |
| US-7419709-B2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| US-20080160166-A1 | POLYMER COATING FOR MEDICAL DEVICES | RYPACEK FRANTISEK | 2008-07-03 | — | — | US | disclosed |
| EP-1937328-A1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS, INC. (US) | 2008-07-02 | — | — | EP | disclosed |
| US-7364768-B2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2008-04-29 | — | — | US | disclosed |
| WO-2007041972-A1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS, INC. (US) | 2007-04-19 | — | — | WO | disclosed |
| US-20070071926-A1 | Polymer coating for medical devices | RYPACEK FRANTISEK | 2007-03-29 | — | — | US | disclosed |
| US-20070071879-A1 | Polymer coating for medical devices | RYPACEK FRANTISEK | 2007-03-29 | — | — | US | disclosed |
| EP-1764118-A2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2007-03-21 | — | — | EP | disclosed |
| US-7160592-B2 | Polymer coating for medical devices | CV THERAPEUTICS, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| EP-1492581-B1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS INC (US) | 2006-12-20 | — | — | EP | disclosed |
| US-20060093771-A1 | Polymer coating for medical devices | CV THERAPEUTICS, INC. | 2006-05-04 | — | — | US | disclosed |
| EP-1492581-A1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS, INC. (US) | 2005-01-05 | — | — | EP | disclosed |
| US-20030219562-A1 | Polymer coating for medical devices | CV THERAPEUTICS, INC. | 2003-11-27 | — | — | US | disclosed |
| WO-2003068289-A1 | POLYMER COATING FOR MEDICAL DEVICES | CV THERAPEUTICS, INC. (US) | 2003-08-21 | — | — | WO | disclosed |