Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201638 | 0.95 | TDP1 (0.63) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL1249823 | 0.95 | TDP1 (0.63) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL7529428 | 0.93 | TDP1 (0.61) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL27523804 | 0.93 | TDP1 (0.61) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL27680663 | 0.93 | TDP1 (0.61) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11878683 | 0.93 | TDP1 (0.61) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL28150143 | 0.93 | TDP1 (0.61) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL244587 | 0.90 | TDP1 (0.60) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| Ethylene Glycol SCHEMBL5935819 | 0.90 | TDP1 (0.66) | TDP1MAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL16041456 | 0.88 | TDP1 (0.76) | TDP1ALDH1A1LMNATSHRESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284401-B2 | Process for the preparation of polyether-ester polyols | BAYER MATERIALSCIENCE LLC (US) | 2016-03-15 | — | — | US | disclosed |
| US-8716515-B2 | Process for the preparation of polyether ester polyols | BAYER MATERIALSCIENCE AG (DE) | 2014-05-06 | — | — | US | disclosed |
| US-20100099788-A1 | PROCESS FOR THE PREPARATION OF POLYETHER ESTER POLYOLS | BAYER MATERIALSCIENCE AG (DE) | 2010-04-22 | — | — | US | disclosed |
| EP-1923417-B1 | Process for the preparation of polyether-ester polyols | BAYER MATERIALSCIENCE AG (DE) | 2009-10-14 | — | — | EP | disclosed |
| EP-1923417-A1 | Process for the preparation of polyether-ester polyols | Bayer MaterialScience AG (DE) | 2008-05-21 | — | — | EP | disclosed |
| US-20080114086-A1 | Process for the preparation of polyether-ester polyols | BAYER MATERIALSCIENCE LLC | 2008-05-15 | — | — | US | disclosed |