SCHEMBL3679748

SCHEMBL3679748

O=C[C@H]1CCCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348693 1.00
SCHEMBL4955062 1.00
Hydrochloric Acid SCHEMBL21056373 0.97 SLC6A2 (0.33)
Hydrochloric Acid SCHEMBL17713614 0.97
Hydrochloric Acid SCHEMBL29951921 0.97
SCHEMBL82935 0.97
SCHEMBL158979 0.97 SLC6A2 (0.33)
Hydrochloric Acid SCHEMBL21056379 0.97 SLC6A2 (0.33)
Hydrochloric Acid SCHEMBL21056375 0.97 SLC6A2 (0.33)
SCHEMBL518835 0.97 SLC6A2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210371422-A1 MORPHINAN DERIVATIVE NIPPON CHEMIPHAR CO., LTD. (JP) 2021-12-02 US claimed
EP-3498711-A1 MORPHINAN DERIVATIVE Nippon Chemiphar Co., Ltd. (JP) 2019-06-19 EP claimed
EP-1915149-B1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AETERNA ZENTARIS GMBH (DE) 2018-10-10 EP claimed
CN-103304538-B Method for synthesizing dextromefloquine FOURTH MILITARY MEDICAL UNIV 2014-12-24 CN claimed
US-8710089-B2 Triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2014-04-29 US claimed
CN-103304538-A Method for synthesizing dextromefloquine FOURTH MILITARY MEDICAL UNIV 2013-09-18 CN claimed
US-20100331343-A1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ZENTARIS GMBH (DE) 2010-12-30 US claimed
US-20090042905-A1 TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS AETERNA ZENTARIS GMBH (DE) 2009-02-12 US claimed
EP-1915149-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AEterna Zentaris GmbH (DE) 2008-04-30 EP claimed
US-20070208061-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ZENTARIS GMBH (DE) 2007-09-06 US claimed
WO-2007020013-A2 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS ÆTERNA ZENTARIS GMBH (DE) 2007-02-22 WO claimed
US-20070037857-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2007-02-15 US claimed
CN-1268636-C Dolastatin 15 derivatives ABSF AG (DE) 2006-08-09 CN claimed
CN-1264388-A Dolastatin 15 derivatives ABSF AG (DE) 2000-08-23 CN claimed
US-20210371422-A1 MORPHINAN DERIVATIVE NIPPON CHEMIPHAR CO., LTD. (JP) 2021-12-02 US disclosed
EP-3498711-A1 MORPHINAN DERIVATIVE Nippon Chemiphar Co., Ltd. (JP) 2019-06-19 EP disclosed
EP-1915149-B1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AETERNA ZENTARIS GMBH (DE) 2018-10-10 EP disclosed
US-20070037857-A1 Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors ZENTARIS GMBH (DE) 2007-02-15 US disclosed
CN-1268636-C Dolastatin 15 derivatives ABSF AG (DE) 2006-08-09 CN disclosed
CN-1264388-A Dolastatin 15 derivatives ABSF AG (DE) 2000-08-23 CN disclosed