SCHEMBL3679867

SCHEMBL3679867

C=C([C]=O)c1c[nH]cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16850631 0.73
SCHEMBL10403535 0.71
SCHEMBL17832467 0.71
SCHEMBL1270987 0.71
SCHEMBL307413 0.71
SCHEMBL12517978 0.70
SCHEMBL4445528 0.67
SCHEMBL343264 0.67
4-Imidazolecarboxylic Acid SCHEMBL10564448 0.67
SCHEMBL669943 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062240-B1 N-TERMINALLY MODIFIED GLP-1 DERIVATIVES NOVO NORDISK AS (DK) 2010-04-28 EP claimed
US-6458924-B2 POLYPEPTIDE DRUG; ANTIDIABETIC AGENT; Liraglutide NOVO NORDISK A/S (DK) 2002-10-01 US disclosed
EP-0846127-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY Novartis AG (CH) 1998-06-10 EP disclosed
WO-1997008193-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY NOVARTIS AG (CH) 1997-03-06 WO disclosed