Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 11/20 | 0.39 |
| ▸ | FNTB | P49356 | 11/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694212 | 0.84 | FNTA (0.41) | FNTAFNTBALDH1A1KDM4ELMNA | |
| SCHEMBL3500964 | 0.84 | FNTA (0.41) | FNTAFNTBALDH1A1KDM4EMAPT | |
| SCHEMBL3500345 | 0.81 | FNTA (0.50) | FNTAFNTBALDH1A1KDM4EMAPT | |
| SCHEMBL3501379 | 0.80 | FNTA (0.44) | FNTAFNTBALDH1A1TSHR | |
| SCHEMBL3501375 | 0.79 | FNTA (0.44) | FNTAFNTB | |
| SCHEMBL3501004 | 0.79 | FNTA (0.49) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL3502482 | 0.78 | FNTA (0.52) | FNTAFNTBALDH1A1KDM4EMAPT | |
| SCHEMBL3501599 | 0.78 | FNTA (0.41) | FNTAFNTBHDAC1LMNACYP11B1 | |
| SCHEMBL3502109 | 0.78 | FNTA (0.51) | FNTAFNTBKDM4ECYP11B1CYP11B2 | |
| SCHEMBL3502072 | 0.77 | FNTA (0.46) | FNTAFNTBALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057028-A9 | TREATMENT OF PROTEINOPATHIES USING A FARNESYL TRANSFERASE INHIBITOR | LINK MEDICINE CORPORATION (US) | 2010-09-02 | — | — | WO | disclosed |