Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | C1R | P00736 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882726 | 0.90 | NPC1 (0.58) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL914105 | 0.88 | C1R (0.60) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL29440787 | 0.88 | AKR1C3 (0.54) | NPC1RAB9AMAPTKDM4EHPGD | |
| SCHEMBL61277 | 0.88 | AKR1C3 (0.54) | NPC1RAB9AMAPTKDM4EHPGD | |
| SCHEMBL29440785 | 0.88 | AKR1C3 (0.54) | NPC1RAB9AMAPTKDM4EHPGD | |
| SCHEMBL5775806 | 0.88 | NPC1 (0.50) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL812662 | 0.84 | NPC1 (0.53) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL5842306 | 0.84 | KDM4E (0.57) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL7869611 | 0.82 | NPC1 (0.51) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL4029088 | 0.82 | ELANE (0.58) | NPC1RAB9AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2048201-B1 | RESIN COMPOSITION | TEIJIN CHEMICALS LTD (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-8524824-B2 | Resin composition | TEIJIN CHEMICALS, LTD. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-20100113660-A1 | RESIN COMPOSITION | TEIJIN CHEMICALS, LTD. | 2010-05-06 | — | — | US | disclosed |
| EP-2048201-A1 | RESIN COMPOSITION | Teijin Chemicals, Ltd. (JP) | 2009-04-15 | — | — | EP | disclosed |