Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4257413 | 0.92 | TAAR1 (0.81) | TAAR1 | |
| SCHEMBL3647714 | 0.91 | TAAR1 (0.82) | TAAR1 | |
| SCHEMBL3642495 | 0.91 | TAAR1 (0.79) | TAAR1 | |
| SCHEMBL3645668 | 0.91 | TAAR1 (0.79) | TAAR1 | |
| SCHEMBL4247984 | 0.90 | TAAR1 (0.80) | TAAR1 | |
| SCHEMBL3638734 | 0.89 | TAAR1 (0.82) | TAAR1 | |
| SCHEMBL3645506 | 0.88 | TAAR1 (0.77) | TAAR1 | |
| SCHEMBL3689898 | 0.85 | TAAR1 (0.54) | TAAR1 | |
| SCHEMBL3645707 | 0.84 | TAAR1 (1.00) | TAAR1 | |
| SCHEMBL4254513 | 0.84 | TAAR1 (0.79) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2182935-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. Hoffmann-Roche AG (CH) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |