SCHEMBL3679953

SCHEMBL3679953

CCc1ccc(Cc2cc(Br)c(CO)cc2Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.43
SLC5A1 P13866 10/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3682044 0.89 SLC5A2 (0.42) SLC5A2SLC5A1
SCHEMBL3674512 0.86 SLC5A2 (0.39) SLC5A2SLC5A1
SCHEMBL27792574 0.84 SLC5A2 (0.38) SLC5A2SLC5A1
SCHEMBL3678607 0.84 SLC5A2 (0.48) SLC5A2SLC5A1
SCHEMBL3680179 0.83 SLC5A2 (0.49) SLC5A2SLC5A1
SCHEMBL31026044 0.78 SLC5A2 (0.37) SLC5A2SLC5A1
SCHEMBL3804311 0.77 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL3679434 0.77 SLC5A2 (0.45) SLC5A2SLC5A1
SCHEMBL1315873 0.77 CBFB (0.31)
SCHEMBL1539290 0.77 SLC5A2 (0.52) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019679-B1 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE THERACOS INC (US) 2018-06-20 EP disclosed
EP-2019679-B1 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE THERACOS INC (US) 2018-06-20 EP disclosed
EP-2064222-B1 BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE THERACOS INC (US) 2014-05-07 EP disclosed
EP-2064222-B1 BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE THERACOS INC (US) 2014-05-07 EP disclosed
WO-2013045495-A1 PYRANO[3,2-c][2]BENZOPYRAN-6(2H)-ONE DERIVATIVES AND USES THEREOF PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) 2013-04-04 WO disclosed
WO-2013045495-A1 PYRANO[3,2-c][2]BENZOPYRAN-6(2H)-ONE DERIVATIVES AND USES THEREOF PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) 2013-04-04 WO disclosed
EP-2573088-A1 Pyrano[3,2-c]benzopyran-6(2h)-one derivatives and uses thereof Prous Institute for Biomedical Research, S.A. (ES) 2013-03-27 EP disclosed
EP-2573088-A1 Pyrano[3,2-c]benzopyran-6(2h)-one derivatives and uses thereof Prous Institute for Biomedical Research, S.A. (ES) 2013-03-27 EP disclosed
US-7838498-B2 Benzylic glycoside derivatives and methods of use THERACOS, INC. (US) 2010-11-23 US disclosed
US-7838498-B2 Benzylic glycoside derivatives and methods of use THERACOS, INC. (US) 2010-11-23 US disclosed
WO-2008122014-A1 BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2008-10-09 WO disclosed
WO-2008122014-A1 BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2008-10-09 WO disclosed
US-20080242596-A1 BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2008-10-02 US disclosed
US-20080242596-A1 BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2008-10-02 US disclosed
US-20080242596-A1 BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE THERACOS, INC. (US) 2008-10-02 US disclosed
WO-2007140191-A2 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE THERACOS, INC. (US) 2007-12-06 WO disclosed
WO-2007140191-A2 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE THERACOS, INC. (US) 2007-12-06 WO disclosed
US-20070275907-A1 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE SEED, BRIAN 2007-11-29 US disclosed
US-20070275907-A1 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE SEED, BRIAN 2007-11-29 US disclosed
US-20070275907-A1 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE SEED, BRIAN 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275907-A1 GLUCOSE TRANSPORT INHIBITORS AND METHODS OF USE SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885SLC5A1 1/4885
US-20080242596-A1 BENZYLIC GLYCOSIDE DERIVATIVES AND METHODS OF USE SLC5A2, SLC5A1, SLC2A1 SLC5A2 1/4885SLC5A1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.