SCHEMBL3680722

SCHEMBL3680722

Cc1cc(C(Cc2ccc(O)cc2)c2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 14/20 0.50
ESR2 Q92731 14/20 0.50
TAAR1 Q96RJ0 3/20 0.43
SLC6A2 P23975 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
YARS1 P54577 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4025450 0.93 ESR1 (0.50) ESR1ESR2TAAR1SLC6A2MEN1
SCHEMBL1236965 0.92 ESR1 (0.42) ESR1ESR2SLC6A2
SCHEMBL8357018 0.90 ESR1 (0.53) ESR1ESR2TAAR1SLC6A2MEN1
SCHEMBL1405931 0.89 ESR1 (0.57) ESR1ESR2SLC6A2MEN1ALDH1A1
SCHEMBL29908399 0.88 ESR1 (0.46) ESR1ESR2TAAR1SLC6A2MEN1
SCHEMBL2030097 0.88 ESR1 (0.46) ESR1ESR2TAAR1SLC6A2MEN1
SCHEMBL29204648 0.85 SLC6A4 (0.47) ESR1ESR2SLC6A2MEN1CYP2C9
Bisphenol A SCHEMBL7115738 0.84 ESR1 (0.49) ESR1ESR2SLC6A2ALDH1A1CYP3A4
SCHEMBL2561070 0.83 ESR1 (0.50) ESR1ESR2SLC6A2MEN1ALDH1A1
SCHEMBL8351878 0.83 ESR1 (0.48) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732562-B2 Trisoxetane compound, production process and optical waveguide therewith NITTO DENKO CORPORATION (JP) 2010-06-08 US disclosed
EP-1842849-B1 Trisoxetane compound, process for producing the same, and optical waveguide using the same NITTO DENKO CORP (JP) 2008-10-08 EP disclosed
US-20070237963-A1 Trisoxetane compound, process for producing the same, and optical waveguide using the same NITTO DENKO CORPORATION (JP) 2007-10-11 US disclosed
EP-1842849-A1 Trisoxetane compound, process for producing the same, and optical waveguide using the same NITTO DENKO CORPORATION (JP) 2007-10-10 EP disclosed
EP-0709358-B1 NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIFOULING AGENT NIPPON SODA CO (JP) 1999-10-13 EP disclosed
EP-0816349-A1 NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION CONTAINING SAID NOVEL CLATHRATE COMPOUND ROHM AND HAAS COMPANY (US) 1998-01-07 EP disclosed
EP-0709358-A1 NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIFOULING AGENT NIPPON SODA CO., LTD. (JP) 1996-05-01 EP disclosed