Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3677522 | 0.93 | CYP2D6 (0.43) | CYP2D6CYP2C19CYP1A2KMT2AMEN1 | |
| SCHEMBL4576738 | 0.85 | CYP2D6 (0.48) | CYP2D6CYP2C19CYP1A2KMT2AMEN1 | |
| SCHEMBL1071748 | 0.84 | CYP2C19 (0.40) | CYP2D6CYP2C19CYP1A2KMT2AMEN1 | |
| SCHEMBL30366973 | 0.80 | CYP2D6 (0.53) | CYP2D6CYP2C19CYP1A2KMT2AMEN1 | |
| SCHEMBL15074109 | 0.78 | TSHR (0.46) | CYP2D6CYP2C19CYP1A2KMT2AMEN1 | |
| SCHEMBL7875432 | 0.78 | TSHR (0.52) | CYP2D6CYP2C19KMT2AMEN1LMNA | |
| SCHEMBL1783799 | 0.76 | CYP2D6 (0.58) | CYP2D6CYP2C19CYP1A2KMT2AMEN1 | |
| SCHEMBL31216697 | 0.74 | MEN1 (0.47) | KMT2AMEN1LMNATSHRALOX12 | |
| SCHEMBL31216696 | 0.74 | MEN1 (0.47) | KMT2AMEN1LMNATSHRALOX12 | |
| SCHEMBL31216725 | 0.74 | MEN1 (0.47) | KMT2AMEN1LMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185600-A1 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | Dow Global Technologies Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009029447-A1 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-03-05 | — | — | WO | disclosed |