Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682782 | 0.98 | CYP1A2 (0.47) | CYP1A2SIGMAR1EPHX1GNAI3GNAO1 | |
| SCHEMBL3680465 | 0.98 | CYP1A2 (0.47) | CYP1A2SIGMAR1EPHX1GNAI3GNAO1 | |
| SCHEMBL3677758 | 0.98 | CYP1A2 (0.47) | CYP1A2SIGMAR1EPHX1GNAI3GNAO1 | |
| SCHEMBL3682324 | 0.98 | CYP1A2 (0.47) | CYP1A2SIGMAR1EPHX1GNAI3GNAO1 | |
| SCHEMBL3687668 | 0.98 | CYP1A2 (0.47) | CYP1A2SIGMAR1EPHX1GNAI3GNAO1 | |
| SCHEMBL3239727 | 0.94 | CYP1A2 (0.56) | CYP1A2SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL25666285 | 0.88 | CYP1A2 (0.41) | CYP1A2EPHX1GNAI3GNAO1GNAI1 | |
| SCHEMBL19090014 | 0.85 | CYP1A2 (0.38) | CYP1A2NOS1NOS2 | |
| SCHEMBL3243534 | 0.85 | CYP1A2 (0.38) | CYP1A2NOS1NOS2 | |
| SCHEMBL19090013 | 0.85 | CYP1A2 (0.38) | CYP1A2NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121492-B | Pd catalyzed gamma-C (sp) of free amines 3 ) H arylation/heteroarylation | 斯克利普斯研究院 | 2023-04-28 | — | — | CN | disclosed |
| US-10759743-B2 | Pd-catalyzed γ-C(sp3)-H arylation / heteroarylation of free amines | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-09-01 | — | — | US | disclosed |
| CN-110121492-A | Pd catalyzed gamma-C (sp) of free amines3) -H arylation/heteroarylation | 斯克利普斯研究院 | 2019-08-13 | — | — | CN | disclosed |
| US-20190241508-A1 | PD-CATALYZED GAMMA-C(SP3)-H ARYLATION / HETEROARYLATION OF FREE AMINES | THE SCRIPPS RESEARCH INSTITUTE | 2019-08-08 | — | — | US | disclosed |
| CN-1898317-B | Composition and method for controlling crystallization rate of polyolefin-based resin, resin composition, and resin molded article | NEW JAPAN CHEM CO LTD | 2010-11-24 | — | — | CN | disclosed |
| US-7723413-B2 | Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| EP-1715000-B1 | METHOD AND COMPOSITION FOR CONTROL OF CRYSTALLIZATION RATE OF POLYOLEFIN RESIN, RESIN COMPOSITION AND RESIN MOLDING | NEW JAPAN CHEM CO LTD (JP) | 2010-03-10 | — | — | EP | disclosed |
| EP-2083045-A1 | Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding | New Japan Chemical Co., Ltd. (JP) | 2009-07-29 | — | — | EP | disclosed |
| US-20070142514-A1 | Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-06-21 | — | — | US | disclosed |
| CN-1898317-A | Composition and method for controlling crystallization rate of polyolefin-based resin, resin composition, and resin molded article | NEW JAPAN CHEM CO LTD (JP) | 2007-01-17 | — | — | CN | disclosed |
| EP-1715000-A1 | METHOD AND COMPOSITION FOR CONTROL OF CRYSTALLIZATION RATE OF POLYOLEFIN RESIN, RESIN COMPOSITION AND RESIN MOLDING | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 2006-10-25 | — | — | EP | disclosed |
| EP-0940387-B1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | MITSUBISHI PHARMA CORP (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6069176-A | PHENYLETHANOLAMINE COMPOUNDS WITH A BETA-3 ADRENERGIC RECEPTOR STIMULATING EFFECT, USE AS A THERAPY FOR URINARY INCONTINENCE | MITSUBISHI-TOKYO PHARMACEUTICALS, INC. (JP) | 2000-05-30 | — | — | US | disclosed |
| EP-0940387-A1 | PHENYLETHANOLAMINE COMPOUNDS USEFUL AS BETA3 AGONIST, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATES IN THE PRODUCTION OF THE SAME | TOKYO TANABE COMPANY LIMITED (JP) | 1999-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759743-B2 | Pd-catalyzed γ-C(sp3)-H arylation / heteroarylation of free amines | DBH, GRIA3, H1-3 | CYP1A2 836/4885SIGMAR1 1322/4885EPHX1 3680/4885 |
| US-20190241508-A1 | PD-CATALYZED GAMMA-C(SP3)-H ARYLATION / HETEROARYLATION OF FREE AMINES | DBH, SNCA, H1-3 | CYP1A2 872/4885SIGMAR1 1045/4885EPHX1 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.