Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.31 |
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | PPP2CA | P67775 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16138831 | 1.00 | TP53 (0.31) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL22490620 | 0.79 | TP53 (0.30) | TP53CYP3A4MAPK1HIF1ALMNA | |
| SCHEMBL9971695 | 0.77 | — | — | |
| SCHEMBL13456892 | 0.77 | — | — | |
| SCHEMBL13585292 | 0.77 | — | — | |
| SCHEMBL19228240 | 0.77 | — | — | |
| SCHEMBL4370157 | 0.77 | — | — | |
| SCHEMBL18760699 | 0.77 | — | — | |
| SCHEMBL19663106 | 0.74 | — | — | |
| SCHEMBL1128661 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281068-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITY OF GENEVA | 2009-11-12 | — | — | US | claimed |
| EP-1883665-A2 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITE DE GENEVE (CH) | 2008-02-06 | — | — | EP | claimed |
| WO-2007012979-A2 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITE DE GENEVE (US) | 2007-02-01 | — | — | WO | claimed |
| US-10314913-B2 | Polylactide compositions and uses thereof | UNIVERSITY OF GENEVA (CH) | 2019-06-11 | — | — | US | disclosed |
| US-10314913-B2 | Polylactide compositions and uses thereof | UNIVERSITY OF GENEVA (CH) | 2019-06-11 | — | — | US | disclosed |
| US-20180271984-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITY OF GENEVA (CH) | 2018-09-27 | — | — | US | disclosed |
| EP-3339348-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | Universite De Geneve (CH) | 2018-06-27 | — | — | EP | disclosed |
| EP-3339348-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | Universite De Geneve (CH) | 2018-06-27 | — | — | EP | disclosed |
| US-9925267-B2 | Polylactide compositions and uses thereof | UNIVERSITY OF GENEVA (CH) | 2018-03-27 | — | — | US | disclosed |
| US-9925267-B2 | Polylactide compositions and uses thereof | UNIVERSITY OF GENEVA (CH) | 2018-03-27 | — | — | US | disclosed |
| US-9925267-B2 | Polylactide compositions and uses thereof | UNIVERSITY OF GENEVA (CH) | 2018-03-27 | — | — | US | disclosed |
| US-20090281068-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITY OF GENEVA | 2009-11-12 | — | — | US | disclosed |
| US-20090281068-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITY OF GENEVA | 2009-11-12 | — | — | US | disclosed |
| EP-1883665-A2 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITE DE GENEVE (CH) | 2008-02-06 | — | — | EP | disclosed |
| WO-2007012979-A2 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITE DE GENEVE (US) | 2007-02-01 | — | — | WO | disclosed |
| WO-2007012979-A2 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | UNIVERSITE DE GENEVE (US) | 2007-02-01 | — | — | WO | disclosed |
| US-6469133-B2 | SUCH AS CRYSTALLINE POLYLACTIDE AND POLYMANDELIDE, FROM SUBSTITUTED 1,4-DIOXAN-2,5-DIONES BY MIXING AN ANHYDROUS METAL ORGANIC LIGAND WITH THE DIOXANEDIONE AND HEATING; HIGH MELTING BIODEGRADABLE POLYMERS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2002-10-22 | — | — | US | disclosed |
| US-6372844-B1 | POLYLACTAM BLOCK POLYMERS OR GRAFT POLYMERS AND COPOLYMERS WITH ASPARTIC ACID | MITSUI CHEMICALS, INC. (JP) | 2002-04-16 | — | — | US | disclosed |
| US-20010044514-A1 | Process for the preparation of polymers of dimeric cyclic esters | BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY | 2001-11-22 | — | — | US | disclosed |
| EP-1041118-A2 | Resin composition | Mitsui Chemicals, Inc. (JP) | 2000-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10314913-B2 | Polylactide compositions and uses thereof | LPXN, PUF60, DDOST | TP53 3052/4885CYP3A4 931/4885MAPK1 4596/4885 |
| US-20090281068-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | LPXN, PUF60, DDOST | TP53 3052/4885CYP3A4 931/4885MAPK1 4596/4885 |
| US-20180271984-A1 | POLYLACTIDE COMPOSITIONS AND USES THEREOF | LPXN, PUF60, DDOST | TP53 3052/4885CYP3A4 931/4885MAPK1 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.