Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 18/20 | 0.40 |
| ▸ | MC5R | P33032 | 17/20 | 0.40 |
| ▸ | MC3R | P41968 | 13/20 | 0.40 |
| ▸ | MC1R | Q01726 | 9/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318041 | 0.96 | MC4R (0.46) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL2315570 | 0.96 | MC4R (0.46) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL1307814 | 0.96 | MC4R (0.43) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL1307815 | 0.96 | MC4R (0.43) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL1310141 | 0.96 | MC4R (0.43) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL2315290 | 0.96 | MC4R (0.43) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL1309007 | 0.95 | MC4R (0.42) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL2320057 | 0.94 | MC4R (0.41) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL3805295 | 0.94 | MC4R (0.42) | MC4RMC5RMC3RMC1RHTT | |
| SCHEMBL1308793 | 0.94 | MC4R (0.42) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012131090-A1 | METHOD FOR TREATMENT OF XERODERMA PIGMENTOSUM | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-10-04 | — | — | WO | claimed |
| WO-2010052255-A1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | claimed |
| WO-2012131090-A1 | METHOD FOR TREATMENT OF XERODERMA PIGMENTOSUM | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2012-10-04 | — | — | WO | disclosed |
| WO-2010052255-A1 | MELANOCORTIN RECEPTOR MODULATORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |