SCHEMBL3682968

SCHEMBL3682968

CCOP(=O)(CC[Si](OC)(OC)OC)OCC

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.50
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7594334 0.88 PPARD (0.47) PPARDTSHRTP53TDP1CA12
SCHEMBL2232173 0.83 PPARD (0.50) PPARDTSHRTP53TDP1CA12
SCHEMBL28926765 0.81 PPARD (0.46) PPARDTSHRCA12CA1CA2
SCHEMBL7599396 0.80 PPARD (0.44) PPARDTSHRTP53TDP1CA12
SCHEMBL9506353 0.79
SCHEMBL7599389 0.77 PPARD (0.41) PPARDTSHR
SCHEMBL27658919 0.77 TSHR (0.50) PPARDTSHRTP53TDP1MEN1
SCHEMBL15715829 0.77 PPARD (0.34) PPARDTSHR
SCHEMBL3313657 0.75 PPARD (0.70) PPARDTSHRTP53TDP1MEN1
SCHEMBL7593793 0.74 PPARD (0.50) PPARDTSHRTP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985702-B1 Flame retardant dispersion composition CONSORTIUM ELEKTROCHEM IND (DE) 2002-11-27 EP claimed
US-6111002-A Flame-retardant dispersion composition WACKER-CHEMIE GMBH (DE) 2000-08-29 US claimed
US-8821838-B2 Nanoparticulate compositions for diagnostic imaging GENERAL ELECTRIC COMPANY (US) 2014-09-02 US disclosed
US-8728440-B2 Nanoparticulate compositions for diagnostic imaging GENERAL ELECTRIC COMPANY (US) 2014-05-20 US disclosed
US-20140056819-A1 NANOPARTICULATE COMPOSITIONS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2014-02-27 US disclosed
US-20140056821-A1 NANOPARTICULATE COMPOSITIONS FOR DIAGNOSTIC IMAGING GENERAL ELECTRIC COMPANY (US) 2014-02-27 US disclosed
US-7728159-B2 Organopolysiloxanes containing phosphonic groups, method for the production and use thereof PHOSPHONICS LIMITED (GB) 2010-06-01 US disclosed
US-20060241314-A1 Organopolysiloxanes containing phosphonic groups, method for the production and use thereof PHOSPHONICS LIMITED (GB) 2006-10-26 US disclosed
EP-1360222-B1 ORGANOPOLYSILOXANES CONTAINING PHOSPHONIC GROUPS, METHODS FOR THE PRODUCTION AND USE THEREOF PHOSPHONICS LTD (GB) 2006-09-06 EP disclosed
WO-2004007073-A1 SUPPORTED CATALYST JOHNSON MATTHEY PLC (GB) 2004-01-22 WO disclosed
EP-1360222-A1 ORGANOPOLYSILOXANES CONTAINING PHOSPHONIC GROUPS, METHODS FOR THE PRODUCTION AND USE THEREOF QUEEN MARY & WESTFIELD COLLEGE (GB) 2003-11-12 EP disclosed
WO-2002055587-A1 ORGANOPOLYSILOXANES CONTAINING PHOSPHONIC GROUPS, METHODS FOR THE PRODUCTION AND USE THEREOF QUEEN MARY & WESTFIELD COLLEGE (GB) 2002-07-18 WO disclosed
US-6111002-A Flame-retardant dispersion composition WACKER-CHEMIE GMBH (DE) 2000-08-29 US disclosed
US-4302929-A Hairy monocomponent yarn HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-01 US disclosed
US-4300344-A Feed yarn and process for the manufacture of a voluminous false twist texturized hairy yarn HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-17 US disclosed
US-4021520-A Process for the manufacture of filament yarn having protruding filament ends HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-03 US disclosed
US-3991549-A Filament yarn and process to prepare same HOECHST AKTIENGESELLSCHAFT (DT) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241314-A1 Organopolysiloxanes containing phosphonic groups, method for the production and use thereof ORC3, ROR1, TYK2 PPARD 2829/4885TSHR 2393/4885TP53 2893/4885
US-20140056819-A1 NANOPARTICULATE COMPOSITIONS FOR DIAGNOSTIC IMAGING C1S, C1R, C3AR1 PPARD 4879/4885TSHR 835/4885TP53 1634/4885
US-20140056821-A1 NANOPARTICULATE COMPOSITIONS FOR DIAGNOSTIC IMAGING C1S, C1R, C3AR1 PPARD 4880/4885TSHR 978/4885TP53 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.