Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690537 | 1.00 | TSHR (0.46) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL3684177 | 1.00 | TSHR (0.46) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL1361708 | 0.89 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1MAPT | |
| SCHEMBL3694499 | 0.83 | TSHR (0.43) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL3691633 | 0.83 | TSHR (0.43) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL3693782 | 0.83 | TSHR (0.43) | TSHRIDO1TP53AGXTALDH1A1 | |
| SCHEMBL3694568 | 0.80 | TSHR (0.47) | TSHRIDO1ALDH1A1MAPK1TDP1 | |
| SCHEMBL3685455 | 0.80 | TSHR (0.47) | TSHRIDO1ALDH1A1MAPK1TDP1 | |
| SCHEMBL3693061 | 0.80 | TSHR (0.47) | TSHRIDO1ALDH1A1MAPK1TDP1 | |
| SCHEMBL3687648 | 0.80 | TSHR (0.48) | TSHRIDO1TP53AGXTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1792889-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2015-03-04 | — | — | EP | disclosed |
| EP-1547995-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| CN-1660764-B | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO | 2010-12-08 | — | — | CN | disclosed |
| US-7741511-B2 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | disclosed |
| US-7399873-B2 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-07-15 | — | — | US | disclosed |
| US-20080033194-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | SOUDA HIROSHI | 2008-02-07 | — | — | US | disclosed |
| US-20080009648-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | SOUDA HIROSHI | 2008-01-10 | — | — | US | disclosed |
| EP-1792889-A2 | Process for the preparation of carboxylic acid esters | Sumitomo Chemical Company, Limited (JP) | 2007-06-06 | — | — | EP | disclosed |
| CN-1660764-A | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2005-08-31 | — | — | CN | disclosed |
| EP-1547995-A1 | Process for the preparation of carboxylic acid esters | Sumitomo Chemical Company, Limited (JP) | 2005-06-29 | — | — | EP | disclosed |
| US-20050113581-A1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113581-A1 | Process for the preparation of carboxylic acid esters | ACSL6, ALKBH3, ACSL1 | TSHR 1811/4885IDO1 2623/4885TP53 3860/4885 |
| US-20080033194-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | ACSL6, ALKBH3, ACSL1 | TSHR 1811/4885IDO1 2623/4885TP53 3860/4885 |
| US-20080009648-A1 | PROCESS FOR THE PREPARATION OF CARBOXYLIC ACID ESTERS | ACSL6, ALKBH3, ACSL1 | TSHR 1811/4885IDO1 2623/4885TP53 3860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.