Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692120 | 0.92 | PPARD (0.40) | PPARDPPARAPPARG | |
| SCHEMBL3690235 | 0.90 | PPARD (0.53) | PPARDPPARA | |
| SCHEMBL3686665 | 0.88 | PPARD (0.51) | PPARDPPARA | |
| SCHEMBL3690903 | 0.85 | PPARD (0.57) | PPARDPPARA | |
| SCHEMBL3694047 | 0.83 | PPARD (0.50) | PPARDPPARA | |
| SCHEMBL3686923 | 0.83 | PPARD (0.54) | PPARDPPARA | |
| SCHEMBL3685384 | 0.83 | PPARD (0.56) | PPARDPPARA | |
| SCHEMBL3690259 | 0.83 | PPARD (0.47) | PPARDPPARA | |
| SCHEMBL3679301 | 0.83 | PPARD (0.45) | PPARDPPARA | |
| SCHEMBL3687872 | 0.83 | PPARD (0.43) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655641-B2 | Sulfonamide derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |
| EP-1597248-B1 | SULFONAMIDE DERIVATIVES AS PPAR MODULATORS | LILLY CO ELI (US) | 2007-12-26 | — | — | EP | disclosed |