SCHEMBL3685178

SCHEMBL3685178

CCCCC(C=O)(C=O)CC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
ADH1B P00325 2/20 0.33
ADH1C P00326 2/20 0.33
ADH1A P07327 2/20 0.33
ADH7 P40394 2/20 0.33
FDPS P14324 1/20 0.33
EPHX1 P07099 1/20 0.32
ADH4 P08319 1/20 0.32
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
TRPA1 O75762 1/20 0.31
FAAH O00519 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3082076 0.86 TSHR (0.32) TSHR
Methacrylic Acid SCHEMBL7269981 0.82 TSHR (0.33) TSHRTRPA1
SCHEMBL27514257 0.81 TSHR (0.31) TSHR
SCHEMBL2367754 0.76
SCHEMBL11805769 0.74 TSHR (0.38) TSHRADH1BADH1CADH1AADH7
SCHEMBL9578924 0.74 TSHR (0.38) TSHRADH1BADH1CADH1AADH7
SCHEMBL276807 0.72 TSHR (0.36) TSHRADH1BADH1CADH1AADH7
SCHEMBL11854298 0.72
SCHEMBL1410619 0.70
SCHEMBL9171978 0.70 TSHR (0.39) TSHRADH1BADH1CADH1AADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9982161-B2 Graft copolymers with grafted polymeric arms, their preparation and use DEUCHEM (SHANGHAI) CHEMICAL CO., LTD. (CN) 2018-05-29 US claimed
US-20150105514-A1 GRAFT COPOLYMERS WITH GRAFTED POLYMERIC ARMS, THEIR PREPARATION AND USE DEUCHEM (SHANGHAI) CHEMICAL CO., LTD. (CN) 2015-04-16 US claimed
EP-2814856-A1 GRAFT COPOLYMERS WITH GRAFTED POLYMERIC ARMS, THEIR PREPARATION AND USE Deuchem (Shanghai) Chemical Co., Ltd (CN) 2014-12-24 EP claimed
WO-2013120249-A1 GRAFT COPOLYMERS WITH GRAFTED POLYMERIC ARMS, THEIR PREPARATION AND USE DEUCHEM (SHANGHAI) CHEMICAL CO., LTD. (CN) 2013-08-22 WO claimed
EP-3841177-B1 MOISTURE CURABLE POLYURETHANE ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2025-04-16 EP disclosed
US-11629277-B2 Moisture curable polyurethane adhesive composition HENKEL AG & CO. KGAA (DE) 2023-04-18 US disclosed
EP-3841177-A1 MOISTURE CURABLE POLYURETHANE ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2021-06-30 EP disclosed
US-20210171812-A1 Moisture curable polyurethane adhesive composition HENKEL AG & CO. KGAA (DE) 2021-06-10 US disclosed
WO-2020037581-A1 MOISTURE CURABLE POLYURETHANE ADHESIVE COMPOSITION HENKEL AG & CO. KGAA (DE) 2020-02-27 WO disclosed
US-20150146293-A1 METHOD FOR PRODUCING OPTICAL FILM LAMINATE, THIN POLARIZING FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2015-05-28 US disclosed
EP-2725048-A1 Method for producing a high molecular weight polyester or copolyester and polymer blends containing the same Uhde Inventa-Fischer GmbH (DE) 2014-04-30 EP disclosed
US-20100249291-A1 REACTIVE HOT-MELT COMPOSITION AND MOLDED ARTICLE USING THE SAME UBE INDUSTRIES, LTD. (JP) 2010-09-30 US disclosed
US-4983501-A Water-insoluble binder, compound forming strong acid on irradiation, acetal, relief image formation HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-08 US disclosed