Triethylene Glycol

Triethylene Glycol

SCHEMBL3685291

C1CCCCC1.N.N.OCCOCCOCCO

nearest known ligand 0.73

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
TSHR P16473 2/20 0.67
MAPK1 P28482 1/20 0.67
THRB P10828 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 1/20 0.45
APP P05067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL27787404 0.97 MEN1 (0.79) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL17555610 0.97 MEN1 (0.79) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL22685881 0.93 MEN1 (0.73) MEN1KMT2ATSHRMAPK1THRB
Di(Hydroxyethyl)Ether SCHEMBL7805707 0.93 TSHR (0.77) MEN1KMT2ATSHRMAPK1THRB
Di(Hydroxyethyl)Ether SCHEMBL4971953 0.90 TSHR (0.71) MEN1KMT2ATSHRMAPK1THRB
Di(Hydroxyethyl)Ether SCHEMBL7598167 0.90 TSHR (0.71) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL11552982 0.89 MEN1 (0.92) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL324028 0.89 MEN1 (0.92) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL43068 0.89 MEN1 (0.92) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL379094 0.89 MEN1 (0.92) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1558672-B1 RAPIDLY LOW TEMPERATURE CURABLE HIGH GAS BARRIER COATING DU PONT (US) 2010-02-10 EP disclosed
US-7072248-B2 Oxygen, carbon dioxide and water vapor impervious multilayers comprising mixtures of binders, minerals, boric acid and mannitol, used as thin films or geometric shaped packages E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-07-04 US disclosed
EP-1558672-A1 RAPIDLY LOW TEMPERATURE CURABLE HIGH GAS BARRIER COATING E.I. du Pont de Nemours and Company (US) 2005-08-03 EP disclosed
US-20040087696-A1 Rapidly low temperature curable high gas barrier coating PERFORMANCE MATERIALS NA, INC. 2004-05-06 US disclosed
WO-2004022635-A1 RAPIDLY LOW TEMPERATURE CURABLE HIGH GAS BARRIER COATING E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-18 WO disclosed