Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL29098329 | 0.98 | APP (0.47) | APPMAPTGAAL3MBTL1ALDH1A1 | |
| SCHEMBL6323843 | 0.86 | APP (0.46) | APPMAPTGAAL3MBTL1ALDH1A1 | |
| SCHEMBL1161861 | 0.85 | APP (0.55) | APPMAPTGAAL3MBTL1ALDH1A1 | |
| SCHEMBL10499366 | 0.83 | PRSS1 (0.47) | APPMAPTGAAL3MBTL1ALDH1A1 | |
| SCHEMBL1947326 | 0.78 | MEN1 (0.47) | MAPTGAAALDH1A1MEN1HPGD | |
| SCHEMBL271536 | 0.78 | APP (0.50) | APPMAPTGAAL3MBTL1ALDH1A1 | |
| SCHEMBL1950296 | 0.78 | MAPT (0.42) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1947650 | 0.77 | MAPT (0.38) | MAPTGAAMEN1KMT2AAGER | |
| SCHEMBL16245938 | 0.76 | APP (0.48) | APPMAPTGAAL3MBTL1ALDH1A1 | |
| SCHEMBL1950132 | 0.76 | MAPT (0.41) | APPMAPTGAAALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574960-B | Docetaxel derivative and preparation method and application thereof | 南京友怡医药科技有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-118076388-A | Carrier for targeting beta-D-N-acetylglucosaminidase | 国家科学研究中心 | 2024-05-24 | — | — | CN | disclosed |
| CN-109574960-B | Docetaxel derivative and preparation method and application thereof | 南京友怡医药科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-114173877-A | Novel therapeutic carriers and prodrugs for the treatment of cancer | 施科友智能化学疗法公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-110845452-A | Cabazitaxel derivative and preparation method and application thereof | 南京友怡医药科技有限公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-107835817-A | Esters of steroid amides and bis (2-chloroethyl) aminophenoxypropionic acid derivatives | 格林尼卡股份公司 | 2018-03-23 | — | — | CN | disclosed |
| CN-105693673-B | Containing 2,4 dinitrobenzenesulfonyl coumarin kind compounds and preparation method and application | 华东理工大学 | 2017-11-14 | — | — | CN | disclosed |
| EP-2173385-A1 | CHLOROTOXINS AS DRUG CARRIERS | Transmolecular, Inc. (US) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009021136-A1 | CHLOROTOXINS AS DRUG CARRIERS | TRANSMOLECULAR, INC. (US) | 2009-02-12 | — | — | WO | disclosed |
| CN-1188134-C | Preparation having increased in vivo tolerability | HOECHST AG (DE) | 2005-02-09 | — | — | CN | disclosed |
| CN-1168733-C | Novel prodrugs for therapy of tumors and inflammatory disorders | ���ĵ�˹ҩ��¹�����˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1095677-C | Compound (I) | ZENECA LTD (GB) | 2002-12-11 | — | — | CN | disclosed |
| US-6303569-B1 | POLYMERIC-BASED DOUBLE PRODRUGS HAVING REVERSIBLE LINKAGES INVOLVING AMINO OR HYDROXYL MOIETIES OF CHEMICAL COMPOUNDS AND BIOLOGICALLY ACTIVE MATERIALS SUCH AS ENZYMES, PROTEINS | ENZON, INC. | 2001-10-16 | — | — | US | disclosed |
| CN-1199613-A | Preparation having increased in vivo tolerability | HOECHST AG (DE) | 1998-11-25 | — | — | CN | disclosed |
| CN-1171054-A | Compound (I) | ZENECA LTD (GB) | 1998-01-21 | — | — | CN | disclosed |
| CN-1163895-A | Novel prodrugs for therapy of tumors and inflammatory disorders | HOECHST AG (DE) | 1997-11-05 | — | — | CN | disclosed |